FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994501339> ?p ?o ?g. }

• W1994501339 endingPage "522" @default.
• W1994501339 startingPage "514" @default.
• W1994501339 abstract "Abstract Aim: The objective of this study was to evaluate the effects of enamel matrix derivative (EMD), transforming growth factor‐ β 1 (TGF‐ β 1), and a combination of both factors (EMD+TGF‐ β 1) on periodontal ligament (PDL) fibroblasts. Material and methods: Human PDL fibroblasts were obtained from three adult patients with a clinically healthy periodontium, using the explant technique. The effects of EMD, TGF‐ β 1, or a combination of both were analysed on PDL cell proliferation, adhesion, wound healing, and total protein synthesis, and on alkaline phosphatase (ALP) activity and bone‐like nodule formation. Results: Treatment with EMD for 4, 7, and 10 days increased cell proliferation significantly compared with the negative control ( p <0.05). At day 10, EMD and EMD+TGF‐ β 1 showed a higher cell proliferation compared with TGF‐ β 1 ( p <0.01). Cell adhesion was significantly up‐regulated by TGF‐ β 1 compared with EMD and EMD+TGF‐ β 1 ( p <0.01). EMD enhanced in vitro wound healing of PDL cells compared with the other treatments. Total protein synthesis was significantly increased in PDL cells cultured with EMD compared with PDL cells treated with TGF‐ β 1 or EMD+TGF‐ β 1 ( p <0.05). EMD induced ALP activity in PDL fibroblasts, which was associated with an increase of bone‐like nodules. Conclusion: These findings support the hypothesis that EMD and TGF‐ β 1 may play an important role in periodontal regeneration. EMD induced PDL fibroblast proliferation and migration, total protein synthesis, ALP activity, and mineralization, while TGF‐ β 1 increased cellular adhesion. However, the combination of both factors did not positively alter PDL fibroblast behaviour." @default.
• W1994501339 created "2016-06-24" @default.
• W1994501339 creator A5000037002 @default.
• W1994501339 creator A5017784202 @default.
• W1994501339 creator A5019102560 @default.
• W1994501339 creator A5022174074 @default.
• W1994501339 creator A5029843488 @default.
• W1994501339 creator A5042980990 @default.
• W1994501339 creator A5045716138 @default.
• W1994501339 creator A5048350882 @default.
• W1994501339 date "2007-05-14" @default.
• W1994501339 modified "2023-10-14" @default.
• W1994501339 title "Effects of enamel matrix derivative and transforming growth factor-?1 on human periodontal ligament fibroblasts" @default.
• W1994501339 cites W1524114372 @default.
• W1994501339 cites W1775749144 @default.
• W1994501339 cites W1974154033 @default.
• W1994501339 cites W1974693246 @default.
• W1994501339 cites W1976937182 @default.
• W1994501339 cites W1989184374 @default.
• W1994501339 cites W1990597486 @default.
• W1994501339 cites W1992599085 @default.
• W1994501339 cites W1999210803 @default.
• W1994501339 cites W2008315456 @default.
• W1994501339 cites W2009915497 @default.
• W1994501339 cites W2018647098 @default.
• W1994501339 cites W2023847589 @default.
• W1994501339 cites W2026863358 @default.
• W1994501339 cites W2030783418 @default.
• W1994501339 cites W2048478219 @default.
• W1994501339 cites W2051331754 @default.
• W1994501339 cites W2054294621 @default.
• W1994501339 cites W2054778734 @default.
• W1994501339 cites W2054956946 @default.
• W1994501339 cites W2058528358 @default.
• W1994501339 cites W2059125062 @default.
• W1994501339 cites W2068741867 @default.
• W1994501339 cites W2075319426 @default.
• W1994501339 cites W2078818259 @default.
• W1994501339 cites W2086731325 @default.
• W1994501339 cites W2089386111 @default.
• W1994501339 cites W2101309683 @default.
• W1994501339 cites W2105758061 @default.
• W1994501339 cites W2106727912 @default.
• W1994501339 cites W2108104357 @default.
• W1994501339 cites W2120123055 @default.
• W1994501339 cites W2130505599 @default.
• W1994501339 cites W2131211068 @default.
• W1994501339 cites W2138819920 @default.
• W1994501339 cites W2144999381 @default.
• W1994501339 cites W2152378536 @default.
• W1994501339 cites W2166497857 @default.
• W1994501339 cites W2168590922 @default.
• W1994501339 cites W2270571149 @default.
• W1994501339 cites W2297594805 @default.
• W1994501339 cites W3141242786 @default.
• W1994501339 cites W4238873679 @default.
• W1994501339 doi "https://doi.org/10.1111/j.1600-051x.2007.01090.x" @default.
• W1994501339 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17509092" @default.
• W1994501339 hasPublicationYear "2007" @default.
• W1994501339 type Work @default.
• W1994501339 sameAs 1994501339 @default.
• W1994501339 citedByCount "57" @default.
• W1994501339 countsByYear W19945013392012 @default.
• W1994501339 countsByYear W19945013392013 @default.
• W1994501339 countsByYear W19945013392014 @default.
• W1994501339 countsByYear W19945013392015 @default.
• W1994501339 countsByYear W19945013392016 @default.
• W1994501339 countsByYear W19945013392017 @default.
• W1994501339 countsByYear W19945013392018 @default.
• W1994501339 countsByYear W19945013392019 @default.
• W1994501339 countsByYear W19945013392020 @default.
• W1994501339 countsByYear W19945013392021 @default.
• W1994501339 countsByYear W19945013392022 @default.
• W1994501339 crossrefType "journal-article" @default.
• W1994501339 hasAuthorship W1994501339A5000037002 @default.
• W1994501339 hasAuthorship W1994501339A5017784202 @default.
• W1994501339 hasAuthorship W1994501339A5019102560 @default.
• W1994501339 hasAuthorship W1994501339A5022174074 @default.
• W1994501339 hasAuthorship W1994501339A5029843488 @default.
• W1994501339 hasAuthorship W1994501339A5042980990 @default.
• W1994501339 hasAuthorship W1994501339A5045716138 @default.
• W1994501339 hasAuthorship W1994501339A5048350882 @default.
• W1994501339 hasConcept C106487976 @default.
• W1994501339 hasConcept C118131993 @default.
• W1994501339 hasConcept C1491633281 @default.
• W1994501339 hasConcept C160160445 @default.
• W1994501339 hasConcept C171056886 @default.
• W1994501339 hasConcept C181199279 @default.
• W1994501339 hasConcept C185592680 @default.
• W1994501339 hasConcept C199343813 @default.
• W1994501339 hasConcept C202751555 @default.
• W1994501339 hasConcept C203014093 @default.
• W1994501339 hasConcept C2778185831 @default.
• W1994501339 hasConcept C2778380114 @default.
• W1994501339 hasConcept C2780269544 @default.
• W1994501339 hasConcept C2780381497 @default.
• W1994501339 hasConcept C41868710 @default.
• W1994501339 hasConcept C43617362 @default.

• next