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- W1994538247 abstract "Plasma homovanillic acid (pHVA) was measured over a 13 hr-period in 16 DMS-III-R schizophrenic patients, all treated with neuroleptic drugs and in a stable clinical and therapeutic status for the preceeding 12 months. Patients were categorized into deficit(n=9) and nondeficit (n=7) forms of schizophrenia according to the Schedule for the Deficit Syndrome (SDS) criteria. As compared to the nondeficit group, deficit patients display significantly lower mean pHVA concentrations from 9 am to 12 am and a lack of diurnal variations. None of the demographic, clinical, and therapeutic variables can explain these biological differences. These data suggest a specific biochemical basis for the deficit syndrome of schizophrenia as defined by the SDS criteria, that is, primary, enduring, negative symptoms." @default.
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- W1994538247 date "1994-08-01" @default.
- W1994538247 modified "2023-09-25" @default.
- W1994538247 title "A comparison of plasma homovanillic acid in the deficit and nondeficit subtypes of schizophrenia" @default.
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- W1994538247 doi "https://doi.org/10.1016/0006-3223(94)90604-1" @default.
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