FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994548283> ?p ?o ?g. }

• W1994548283 abstract "The association of the tumor necrosis factor alpha (TNFalpha) -G308A promoter polymorphism with schizophrenia has complemented clinical findings of increased levels of the TNFalpha cytokine in schizophrenic patients, with some support for a functional consequence of the variant. Our previous studies of genetic causes in schizophrenia supported findings of linkage to the major histocompatibility complex (MHC) region where the TNFalpha gene is located as well as association with the -G308A promoter polymorphism. While the common G-allele shows association in our sample, association with the A-allele has been reported by other groups. This suggests linkage disequilibrium (LD) rather than direct involvement in the disorder. In order to define LD of DNA variants with the disorder in this area, we analyzed 36 SNPs in a 165-kb region around this polymorphism. We detected nominally significant associations (P < 0.05) of three markers (including the -G308A promoter polymorphism) and multiple haplotypes with schizophrenia in our sample of 204 families (79 sib-pairs and 125 trios). The association is largely restricted to a 30 kb high LD region/block and should assist in the identification of a schizophrenia susceptibility gene within the block or elsewhere in the MHC." @default.
• W1994548283 created "2016-06-24" @default.
• W1994548283 creator A5031132366 @default.
• W1994548283 creator A5045097461 @default.
• W1994548283 creator A5051454538 @default.
• W1994548283 creator A5065075154 @default.
• W1994548283 creator A5074276013 @default.
• W1994548283 creator A5077506936 @default.
• W1994548283 date "2007-01-01" @default.
• W1994548283 modified "2023-09-23" @default.
• W1994548283 title "Evaluation of association of SNPs in the TNF alpha gene region with schizophrenia" @default.
• W1994548283 cites W1542136448 @default.
• W1994548283 cites W1966922291 @default.
• W1994548283 cites W1967143685 @default.
• W1994548283 cites W1968004796 @default.
• W1994548283 cites W1968923829 @default.
• W1994548283 cites W1983986322 @default.
• W1994548283 cites W1984539244 @default.
• W1994548283 cites W1990375216 @default.
• W1994548283 cites W1992061966 @default.
• W1994548283 cites W1994469616 @default.
• W1994548283 cites W2005062591 @default.
• W1994548283 cites W2018477520 @default.
• W1994548283 cites W2020337399 @default.
• W1994548283 cites W2020822225 @default.
• W1994548283 cites W2024585237 @default.
• W1994548283 cites W2024938068 @default.
• W1994548283 cites W2027975469 @default.
• W1994548283 cites W2031393403 @default.
• W1994548283 cites W2034464736 @default.
• W1994548283 cites W2043813710 @default.
• W1994548283 cites W2052119995 @default.
• W1994548283 cites W2058401000 @default.
• W1994548283 cites W2061542205 @default.
• W1994548283 cites W2063478222 @default.
• W1994548283 cites W2068640448 @default.
• W1994548283 cites W2072465137 @default.
• W1994548283 cites W2074891952 @default.
• W1994548283 cites W2075817888 @default.
• W1994548283 cites W2084283273 @default.
• W1994548283 cites W2086386219 @default.
• W1994548283 cites W2091943217 @default.
• W1994548283 cites W2095803590 @default.
• W1994548283 cites W2096130477 @default.
• W1994548283 cites W2098701094 @default.
• W1994548283 cites W2105042808 @default.
• W1994548283 cites W2107245637 @default.
• W1994548283 cites W2145378546 @default.
• W1994548283 cites W2149368171 @default.
• W1994548283 cites W2152366552 @default.
• W1994548283 cites W2152664025 @default.
• W1994548283 cites W2158262262 @default.
• W1994548283 cites W2165886134 @default.
• W1994548283 cites W2327531414 @default.
• W1994548283 doi "https://doi.org/10.1002/ajmg.b.30451" @default.
• W1994548283 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17171665" @default.
• W1994548283 hasPublicationYear "2007" @default.
• W1994548283 type Work @default.
• W1994548283 sameAs 1994548283 @default.
• W1994548283 citedByCount "21" @default.
• W1994548283 countsByYear W19945482832012 @default.
• W1994548283 countsByYear W19945482832013 @default.
• W1994548283 countsByYear W19945482832014 @default.
• W1994548283 countsByYear W19945482832016 @default.
• W1994548283 countsByYear W19945482832017 @default.
• W1994548283 countsByYear W19945482832018 @default.
• W1994548283 countsByYear W19945482832019 @default.
• W1994548283 crossrefType "journal-article" @default.
• W1994548283 hasAuthorship W1994548283A5031132366 @default.
• W1994548283 hasAuthorship W1994548283A5045097461 @default.
• W1994548283 hasAuthorship W1994548283A5051454538 @default.
• W1994548283 hasAuthorship W1994548283A5065075154 @default.
• W1994548283 hasAuthorship W1994548283A5074276013 @default.
• W1994548283 hasAuthorship W1994548283A5077506936 @default.
• W1994548283 hasConcept C101762097 @default.
• W1994548283 hasConcept C104317684 @default.
• W1994548283 hasConcept C135763542 @default.
• W1994548283 hasConcept C150194340 @default.
• W1994548283 hasConcept C153209595 @default.
• W1994548283 hasConcept C180754005 @default.
• W1994548283 hasConcept C186413461 @default.
• W1994548283 hasConcept C197754878 @default.
• W1994548283 hasConcept C207936829 @default.
• W1994548283 hasConcept C35605836 @default.
• W1994548283 hasConcept C54355233 @default.
• W1994548283 hasConcept C86803240 @default.
• W1994548283 hasConceptScore W1994548283C101762097 @default.
• W1994548283 hasConceptScore W1994548283C104317684 @default.
• W1994548283 hasConceptScore W1994548283C135763542 @default.
• W1994548283 hasConceptScore W1994548283C150194340 @default.
• W1994548283 hasConceptScore W1994548283C153209595 @default.
• W1994548283 hasConceptScore W1994548283C180754005 @default.
• W1994548283 hasConceptScore W1994548283C186413461 @default.
• W1994548283 hasConceptScore W1994548283C197754878 @default.
• W1994548283 hasConceptScore W1994548283C207936829 @default.
• W1994548283 hasConceptScore W1994548283C35605836 @default.
• W1994548283 hasConceptScore W1994548283C54355233 @default.
• W1994548283 hasConceptScore W1994548283C86803240 @default.
• W1994548283 hasLocation W19945482831 @default.
• W1994548283 hasLocation W19945482832 @default.

• next