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- W1994564635 abstract "©2011 Turkish League Against Rheumatism. All rights reserved. Hiperimmunoglobulin D ve periyodik ates sendromu kolesterol ve izoprenoid biyo-sentezinde gorev alan mevalonat kinaz enzimindeki kusura bagli olarak ortaya cikmaktadir. Bu otozomal resesif kalitimla gecmis olan oto-inflamatuvar sendrom tekrarlayan ates ataklari, karin agrisi, lenfadenopati, cilt lezyonlari ve eklem tutulumu ile karakterizedir. Bu yazida periyodik ates ve hiperimmunoglobulin D sendromu tanisi ile klinigimizde izlenmekte olan 12 yasindaki bir erkek cocugunda hipolipidemik ajan simvastatin ile uyguladigimiz tedavi yaklasimi sunuldu. Hiperimmunoglobulin D ve periyodik ates sendromu olan ve diger antiinflamatuvar tedavilere yanit vermeyen bir adolesanda simvastatin tedavisi ile klinik duzelme gozlendi. Bu tedavinin mevalonik asit artisini veya izoprenoid azligini engelleyerek tekrarlayan ates ataklarini azalttigi dusunuldu." @default.
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- W1994564635 date "2011-06-15" @default.
- W1994564635 modified "2023-10-03" @default.
- W1994564635 title "An Adolescent with Hyperimmunoglobulinemia D and Periodic Fever Syndrome Responding to Simvastatin Treatment" @default.
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- W1994564635 doi "https://doi.org/10.5152/tjr.2011.026" @default.
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