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• W1994582812 abstract "Introduction: Gallbladder cancer is a relatively rare cancer in the United States and is often associated with poor prognosis. We reviewed our experience with treating gallbladder cancer and attempted to identify if demographic, tumor, or surgical factors affected survival in our patient population. Methods: We performed a chart review of the cancer registry of 2 large academic hospitals to identify patients with gallbladder cancer between 1999 and 2007. Demographic information, patient and tumor factors, and survival outcomes were collected. We analyzed the patient population for the impact of patient factors and surgical therapy on survival outcome. Results: Our patient database consisted of 68 patients, 52 of which were women (76%). The ethnic distribution was 37% Hispanic, 34% Caucasian, and 21% African/African-American. The median age at diagnosis was 60 years. The stage distribution for the study group was as follows: Stage I 17%, Stage II 28%, Stage III 11%, and Stage IV 43%. Sixty-two percent (n=42) of patients had their gallbladder removed during treatment, with 25 operations starting as laparoscopic cholecystectomy. Liver resection (radical resection) was performed for 26% (n=16) of patients who had resection of the primary tumor (cholecystectomy). Median follow up was 11 months overall and 17 months for survivors. We identified no difference in survival by race or gender. Median survival for the entire population was 13 months. Stage specific median survival (in months) is as follows: Stage I, II (Early stage) 29; Stage III 14, Stage IV 9 (p<0.01). Grade of the tumor did not affect survival. For patients without metastatic disease (stage I-III), liver resection was associated with improved 2-year survival (36% without liver resection, n=16; 76% with liver resection, n=13; p<0.05). Conclusion: Our data, collected from 2 large teaching hospitals, showed an overall median survival of approximately one year. This is consistent with other reports demonstrating a poor prognosis associated with gallbladder cancer. Surgical treatment, in the form of radical resection, is associated with prolonged survival in patients without distant metastases. These results support the practice of aggressive surgical management for carefully selected patients." @default.
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• W1994582812 date "2010-02-01" @default.
• W1994582812 modified "2023-09-26" @default.
• W1994582812 title "Liver Resection Is Associated with Prolonged Survival for Non-Metastatic Gallbladder Cancer: A 10 Year Review" @default.
• W1994582812 doi "https://doi.org/10.1016/j.jss.2009.11.613" @default.
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