FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994590558> ?p ?o ?g. }

• W1994590558 endingPage "38" @default.
• W1994590558 startingPage "28" @default.
• W1994590558 abstract "We have characterized the changes in tissue concentrations of amino acids and biogenic amines in the central nervous system (CNS) of mice with MOG(35-55)-induced experimental autoimmune encephalomyelitis (EAE), an animal model commonly used to study multiple sclerosis (MS). High performance liquid chromatography was used to analyse tissue samples from five regions of the CNS at the onset, peak and chronic phase of MOG(35-55) EAE. Our analysis includes the evaluation of several newly examined amino acids including d-serine, and the inter-relations between the intraspinal concentration changes of different amino acids and biogenic amines during EAE. Our results confirm many of the findings from similar studies using different variants of the EAE model as well as those examining changes in amino acid and biogenic amine levels in the cerebrospinal fluid (CSF) of MS patients. However, several notable differences were observed between mice with MOG(35-55)-induced EAE with findings from human studies and other EAE models. In addition, our analysis has identified strong correlations between different amino acids and biogenic amines that appear to change in two distinct groups during EAE. Group I analyte concentrations are increased at EAE onset and peak but then decrease in the chronic phase with a large degree of variability. Group II is composed of amino acids and biogenic amines that change in a progressive manner during EAE. The altered levels of these amino acids and biogenic amines in the disease may represent a critical pathway leading to neurodegenerative processes that are now recognized to occur in EAE and MS." @default.
• W1994590558 created "2016-06-24" @default.
• W1994590558 creator A5036716307 @default.
• W1994590558 creator A5058323731 @default.
• W1994590558 creator A5061668278 @default.
• W1994590558 creator A5079451694 @default.
• W1994590558 creator A5088403251 @default.
• W1994590558 date "2011-08-01" @default.
• W1994590558 modified "2023-10-17" @default.
• W1994590558 title "Tissue concentration changes of amino acids and biogenic amines in the central nervous system of mice with experimental autoimmune encephalomyelitis (EAE)" @default.
• W1994590558 cites W1500818454 @default.
• W1994590558 cites W1587255993 @default.
• W1994590558 cites W1589688567 @default.
• W1994590558 cites W1967536482 @default.
• W1994590558 cites W1969093378 @default.
• W1994590558 cites W1969307826 @default.
• W1994590558 cites W1972077846 @default.
• W1994590558 cites W197245174 @default.
• W1994590558 cites W1977472501 @default.
• W1994590558 cites W1978708165 @default.
• W1994590558 cites W1981029525 @default.
• W1994590558 cites W1982061125 @default.
• W1994590558 cites W1983519246 @default.
• W1994590558 cites W1986913568 @default.
• W1994590558 cites W1988167173 @default.
• W1994590558 cites W1992618327 @default.
• W1994590558 cites W1993918716 @default.
• W1994590558 cites W2001079270 @default.
• W1994590558 cites W2015270042 @default.
• W1994590558 cites W2021568221 @default.
• W1994590558 cites W2021688007 @default.
• W1994590558 cites W2022941750 @default.
• W1994590558 cites W2027671137 @default.
• W1994590558 cites W2029669444 @default.
• W1994590558 cites W2038911566 @default.
• W1994590558 cites W2047676079 @default.
• W1994590558 cites W2053929698 @default.
• W1994590558 cites W2055839901 @default.
• W1994590558 cites W2057450652 @default.
• W1994590558 cites W2064953858 @default.
• W1994590558 cites W2069583908 @default.
• W1994590558 cites W2070178074 @default.
• W1994590558 cites W2071623385 @default.
• W1994590558 cites W2072010309 @default.
• W1994590558 cites W2081800309 @default.
• W1994590558 cites W2082363371 @default.
• W1994590558 cites W2082609535 @default.
• W1994590558 cites W2086774548 @default.
• W1994590558 cites W2099232685 @default.
• W1994590558 cites W2107801397 @default.
• W1994590558 cites W2107925005 @default.
• W1994590558 cites W2108335498 @default.
• W1994590558 cites W2111641406 @default.
• W1994590558 cites W2114577257 @default.
• W1994590558 cites W2134122323 @default.
• W1994590558 cites W2140830894 @default.
• W1994590558 cites W3028127986 @default.
• W1994590558 cites W4232468218 @default.
• W1994590558 cites W2035154835 @default.
• W1994590558 doi "https://doi.org/10.1016/j.neuint.2011.03.020" @default.
• W1994590558 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21672584" @default.
• W1994590558 hasPublicationYear "2011" @default.
• W1994590558 type Work @default.
• W1994590558 sameAs 1994590558 @default.
• W1994590558 citedByCount "24" @default.
• W1994590558 countsByYear W19945905582012 @default.
• W1994590558 countsByYear W19945905582013 @default.
• W1994590558 countsByYear W19945905582014 @default.
• W1994590558 countsByYear W19945905582015 @default.
• W1994590558 countsByYear W19945905582016 @default.
• W1994590558 countsByYear W19945905582017 @default.
• W1994590558 countsByYear W19945905582018 @default.
• W1994590558 countsByYear W19945905582019 @default.
• W1994590558 countsByYear W19945905582020 @default.
• W1994590558 countsByYear W19945905582021 @default.
• W1994590558 countsByYear W19945905582022 @default.
• W1994590558 countsByYear W19945905582023 @default.
• W1994590558 crossrefType "journal-article" @default.
• W1994590558 hasAuthorship W1994590558A5036716307 @default.
• W1994590558 hasAuthorship W1994590558A5058323731 @default.
• W1994590558 hasAuthorship W1994590558A5061668278 @default.
• W1994590558 hasAuthorship W1994590558A5079451694 @default.
• W1994590558 hasAuthorship W1994590558A5088403251 @default.
• W1994590558 hasConcept C126322002 @default.
• W1994590558 hasConcept C134018914 @default.
• W1994590558 hasConcept C185592680 @default.
• W1994590558 hasConcept C203014093 @default.
• W1994590558 hasConcept C2776219046 @default.
• W1994590558 hasConcept C2777899865 @default.
• W1994590558 hasConcept C2778377861 @default.
• W1994590558 hasConcept C2778486448 @default.
• W1994590558 hasConcept C2779651940 @default.
• W1994590558 hasConcept C2780640218 @default.
• W1994590558 hasConcept C515207424 @default.
• W1994590558 hasConcept C529278444 @default.
• W1994590558 hasConcept C55493867 @default.
• W1994590558 hasConcept C71924100 @default.
• W1994590558 hasConcept C86803240 @default.

• next