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- W1994608328 abstract "Determinations of red cell volumes, plasma proteins, blood volumes and water balance were made in a low pressure chamber at 435–450 mm Hg barometric pressure. It was found that the increase in cell volume – and O2-capacity – during the first days at low pressure was due to a diminished plasma volume, and paralleled by an increase in plasma protein concentration. A similar concentration of the blood was found during fasting (40 hours) at normal barometric pressure, but a much greater concentration of the blood was observed when the subjects fasted at low barometric pressure. In two of the three subjects the increased concentration of the blood at low pressure was accompanied by an extra loss of water from the body. From an estimation of the part played by the extracellular water in this loss, it was found, that about one half of the concentration of the blood was caused by loss of extracellular body water. The other part of the concentration of the blood – and, in the third subject, the whole extra concentration at low pressure – was due to a leaking-out of fluid from the capillaries, presumably caused by the increased capillary blood pressure and an increased permeability of the capillary walls at low O2,-pressure. While the excess filtration out of the blood no doubt is a sign of insufficiency of the capillaries, incidentally increasing the oxygen capacity of the blood, it is difficult to decide whether the excess excretion of water (increased diuresis) is the result of a regulation, serving the oxygen supply, or whether it is due to other causes." @default.
- W1994608328 created "2016-06-24" @default.
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- W1994608328 date "1945-01-01" @default.
- W1994608328 modified "2023-10-10" @default.
- W1994608328 title "Studies on the Initial Increase in O<sub>2</sub>-capacity of the Blood at Low O<sub>2</sub>-pressure." @default.
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- W1994608328 doi "https://doi.org/10.1111/j.1748-1716.1945.tb03086.x" @default.
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