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- W1994621063 endingPage "046014" @default.
- W1994621063 startingPage "046014" @default.
- W1994621063 abstract "Proteins are large and complex molecular machines. In order to perform their function, most of them need energy, e.g. either in the form of a photon, as in the case of the visual pigment rhodopsin, or through the breaking of a chemical bond, as in the presence of adenosine triphosphate (ATP). Such energy, in turn, has to be transmitted to specific locations, often several tens of A away from where it is initially released. Here we show, within the framework of a coarse-grained nonlinear network model, that energy in a protein can jump from site to site with high yields, covering in many instances remarkably large distances. Following single-site excitations, few specific sites are targeted, systematically within the stiffest regions. Such energy transfers mark the spontaneous formation of a localized mode of nonlinear origin at the destination site, which acts as an efficient energy-accumulating center. Interestingly, yields are found to be optimum for excitation energies in the range of biologically relevant ones." @default.
- W1994621063 created "2016-06-24" @default.
- W1994621063 creator A5060452581 @default.
- W1994621063 creator A5091096024 @default.
- W1994621063 date "2009-11-12" @default.
- W1994621063 modified "2023-10-02" @default.
- W1994621063 title "Long-range energy transfer in proteins" @default.
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- W1994621063 doi "https://doi.org/10.1088/1478-3975/6/4/046014" @default.
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