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• W1994702815 endingPage "1043" @default.
• W1994702815 startingPage "1029" @default.
• W1994702815 abstract "The neuromuscular junction (NMJ) is the synaptic connection between motor neurons and muscle fibers. It is involved in crucial processes such as body movements and breathing. Its proper development requires the guidance of motor axons toward their specific targets, the development of multi-innervated myofibers, and a selective synapse stabilization. It first consists of the removal of excessive motor axons on myofibers, going from multi-innervation to a single innervation of each myofiber. Whereas guidance cues of motor axons toward their specific muscular targets are well characterized, only few molecular and cellular cues have been reported as clues for selecting and stabilizing specific neuromuscular junctions. We will first provide a brief summary on NMJ development. We will then review molecular cues that are involved in NMJ stabilization, in both pre- and post-synaptic compartments, considering motor neurons and Schwann cells on the one hand, and muscle on the other hand. We will provide links with pathologies and highlight advances that can be brought both by basic research on NMJ development and clinical data resulting from the analyses of neurodegeneration of synaptic connections to obtain a better understanding of this process. The goal of this review is to highlight the findings toward understanding the roles of poly- or single-innervations and the underlying mechanisms of NMJ stabilization." @default.
• W1994702815 created "2016-06-24" @default.
• W1994702815 creator A5073420011 @default.
• W1994702815 date "2014-10-31" @default.
• W1994702815 modified "2023-10-09" @default.
• W1994702815 title "Mechanisms controlling neuromuscular junction stability" @default.
• W1994702815 cites W1491433834 @default.
• W1994702815 cites W1782689717 @default.
• W1994702815 cites W1963853740 @default.
• W1994702815 cites W1965170304 @default.
• W1994702815 cites W1973109495 @default.
• W1994702815 cites W1974702055 @default.
• W1994702815 cites W1976438877 @default.
• W1994702815 cites W1978370395 @default.
• W1994702815 cites W1979055602 @default.
• W1994702815 cites W1979060547 @default.
• W1994702815 cites W1979355065 @default.
• W1994702815 cites W1979883968 @default.
• W1994702815 cites W1980294445 @default.
• W1994702815 cites W1980783188 @default.
• W1994702815 cites W1981585359 @default.
• W1994702815 cites W1982387497 @default.
• W1994702815 cites W1982623873 @default.
• W1994702815 cites W1982630660 @default.
• W1994702815 cites W1986172830 @default.
• W1994702815 cites W1991343953 @default.
• W1994702815 cites W1995185770 @default.
• W1994702815 cites W2002699122 @default.
• W1994702815 cites W2005087727 @default.
• W1994702815 cites W2005984686 @default.
• W1994702815 cites W2007502272 @default.
• W1994702815 cites W2021131295 @default.
• W1994702815 cites W2023812792 @default.
• W1994702815 cites W2025922826 @default.
• W1994702815 cites W2031075742 @default.
• W1994702815 cites W2032273931 @default.
• W1994702815 cites W2039431039 @default.
• W1994702815 cites W2041519111 @default.
• W1994702815 cites W2044634543 @default.
• W1994702815 cites W2046098644 @default.
• W1994702815 cites W2046668530 @default.
• W1994702815 cites W2049049008 @default.
• W1994702815 cites W2056729628 @default.
• W1994702815 cites W2059243702 @default.
• W1994702815 cites W2059473556 @default.
• W1994702815 cites W2066335707 @default.
• W1994702815 cites W2068031262 @default.
• W1994702815 cites W2070720564 @default.
• W1994702815 cites W2071712734 @default.
• W1994702815 cites W2074041604 @default.
• W1994702815 cites W2077470457 @default.
• W1994702815 cites W2086143132 @default.
• W1994702815 cites W2088009451 @default.
• W1994702815 cites W2090893026 @default.
• W1994702815 cites W2091044189 @default.
• W1994702815 cites W2098341193 @default.
• W1994702815 cites W2099577539 @default.
• W1994702815 cites W2105536667 @default.
• W1994702815 cites W2107315373 @default.
• W1994702815 cites W2112240787 @default.
• W1994702815 cites W2113284238 @default.
• W1994702815 cites W2113423784 @default.
• W1994702815 cites W2114892569 @default.
• W1994702815 cites W2117911000 @default.
• W1994702815 cites W2119527348 @default.
• W1994702815 cites W2128589265 @default.
• W1994702815 cites W2129584736 @default.
• W1994702815 cites W2129710588 @default.
• W1994702815 cites W2130297788 @default.
• W1994702815 cites W2133762721 @default.
• W1994702815 cites W2134505400 @default.
• W1994702815 cites W2134798771 @default.
• W1994702815 cites W2135146520 @default.
• W1994702815 cites W2135247160 @default.
• W1994702815 cites W2143083824 @default.
• W1994702815 cites W2150947283 @default.
• W1994702815 cites W2154556320 @default.
• W1994702815 cites W2156555464 @default.
• W1994702815 cites W2156806698 @default.
• W1994702815 cites W2158208349 @default.
• W1994702815 cites W2163617647 @default.
• W1994702815 cites W2170178615 @default.
• W1994702815 cites W2397881447 @default.
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• W1994702815 doi "https://doi.org/10.1007/s00018-014-1768-z" @default.
• W1994702815 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25359233" @default.
• W1994702815 hasPublicationYear "2014" @default.
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