Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994706120> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W1994706120 endingPage "562" @default.
- W1994706120 startingPage "556" @default.
- W1994706120 abstract "Analysis of the immune response of a panel of intra-I-region recombinant mouse strains to LDH-B and MOPC-173 demonstrated that B10.ASR7 (H-2±3) and (H-2±4) failed to mount T-cell-proliferative responses to MOPC-173 and LDH-B, respectively. To localize the level of the immune response defect in the B10.BASR1 strain, B10.BASR1 macrophages were shown to be incapable of presenting LDH-B to immune responder B10.ASR7 T cells. These results were confirmed using alloreactivity-depleted and (B10.ASR7xB10.BASR1)F1 immune T cells. Failure of these strains to respond was shown not to be the result of T cell suppression, because cyclophosphamide and anti-Lyt-2.2-plus-complement treatments did not restore responsiveness. Furthermore, B10.BASR1 macrophages were incapable of educating naive responder T cells in vitro to LDH-B—however, naive nonresponder B10.BASR1 T cells could be educated by responder macrophages to LDH-B in vitro. These results suggest that the failure of B10.BASR1 to respond to LDH-B reflects a defect at the macrophage-T cell interaction level, perhaps related to expression of unique I-A molecules created by intra-I-region recombinatorial events." @default.
- W1994706120 created "2016-06-24" @default.
- W1994706120 creator A5065106421 @default.
- W1994706120 creator A5073269496 @default.
- W1994706120 date "1985-11-01" @default.
- W1994706120 modified "2023-10-17" @default.
- W1994706120 title "SEPARATION OF THE IMMUNE RESPONSE GENES FOR LDH-B AND MOPC-173" @default.
- W1994706120 doi "https://doi.org/10.1097/00007890-198511000-00016" @default.
- W1994706120 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2932822" @default.
- W1994706120 hasPublicationYear "1985" @default.
- W1994706120 type Work @default.
- W1994706120 sameAs 1994706120 @default.
- W1994706120 citedByCount "0" @default.
- W1994706120 crossrefType "journal-article" @default.
- W1994706120 hasAuthorship W1994706120A5065106421 @default.
- W1994706120 hasAuthorship W1994706120A5073269496 @default.
- W1994706120 hasBestOaLocation W19947061201 @default.
- W1994706120 hasConcept C153911025 @default.
- W1994706120 hasConcept C159654299 @default.
- W1994706120 hasConcept C202751555 @default.
- W1994706120 hasConcept C203014093 @default.
- W1994706120 hasConcept C2776090121 @default.
- W1994706120 hasConcept C2776694085 @default.
- W1994706120 hasConcept C2776755627 @default.
- W1994706120 hasConcept C2778453870 @default.
- W1994706120 hasConcept C2779244956 @default.
- W1994706120 hasConcept C54355233 @default.
- W1994706120 hasConcept C55493867 @default.
- W1994706120 hasConcept C86803240 @default.
- W1994706120 hasConcept C8891405 @default.
- W1994706120 hasConceptScore W1994706120C153911025 @default.
- W1994706120 hasConceptScore W1994706120C159654299 @default.
- W1994706120 hasConceptScore W1994706120C202751555 @default.
- W1994706120 hasConceptScore W1994706120C203014093 @default.
- W1994706120 hasConceptScore W1994706120C2776090121 @default.
- W1994706120 hasConceptScore W1994706120C2776694085 @default.
- W1994706120 hasConceptScore W1994706120C2776755627 @default.
- W1994706120 hasConceptScore W1994706120C2778453870 @default.
- W1994706120 hasConceptScore W1994706120C2779244956 @default.
- W1994706120 hasConceptScore W1994706120C54355233 @default.
- W1994706120 hasConceptScore W1994706120C55493867 @default.
- W1994706120 hasConceptScore W1994706120C86803240 @default.
- W1994706120 hasConceptScore W1994706120C8891405 @default.
- W1994706120 hasIssue "5" @default.
- W1994706120 hasLocation W19947061201 @default.
- W1994706120 hasLocation W19947061202 @default.
- W1994706120 hasLocation W19947061203 @default.
- W1994706120 hasOpenAccess W1994706120 @default.
- W1994706120 hasPrimaryLocation W19947061201 @default.
- W1994706120 hasRelatedWork W1658359452 @default.
- W1994706120 hasRelatedWork W1968047100 @default.
- W1994706120 hasRelatedWork W1988241479 @default.
- W1994706120 hasRelatedWork W2040938911 @default.
- W1994706120 hasRelatedWork W2046560815 @default.
- W1994706120 hasRelatedWork W2373746689 @default.
- W1994706120 hasRelatedWork W2382086091 @default.
- W1994706120 hasRelatedWork W2409988542 @default.
- W1994706120 hasRelatedWork W2916272666 @default.
- W1994706120 hasRelatedWork W2950289579 @default.
- W1994706120 hasVolume "40" @default.
- W1994706120 isParatext "false" @default.
- W1994706120 isRetracted "false" @default.
- W1994706120 magId "1994706120" @default.
- W1994706120 workType "article" @default.