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- W1994716404 abstract "The neural mechanisms of reactive cutaneous hyperaemia were studied by using a novel experimental approach: the simultaneous measurement of cutaneous blood flow by laser-Doppler flowmetry in adjacent innervated and chemodenervated skin regions of the rat hindpaw served by the same artery. Transient occlusion of the femoral artery (0.5-6 min) resulted in reactive hyperaemia that was greatly reduced in the chemodenervated region. After 3 min arterial occlusion, peak cutaneous blood flow was 109+/-13% vs. 53+/-7%* (% change from baseline, n=11, *P<0.05), and the total hyperaemic response was 110+/-21 vs. 52+/-12* (arbitrary perfusion units) in intact vs. chemodenervated skin regions, respectively. The findings provide clear evidence for the involvement of peptidergic capsaicin-sensitive afferent nerves in the mechanism of reactive cutaneous hyperaemia." @default.
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- W1994716404 date "2003-05-01" @default.
- W1994716404 modified "2023-09-27" @default.
- W1994716404 title "Perineural capsaicin treatment attenuates reactive hyperaemia in the rat skin" @default.
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- W1994716404 doi "https://doi.org/10.1016/s0304-3940(03)00191-5" @default.
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