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- W1994720855 abstract "Mucosal healing has been a central issue in inflammatory bowel disease (IBD) for the last years, and has been proposed to be included as the new treatment goal in IBD. The molecular understanding of both the disruption and the healing of the intestinal epithelial cell lining and the mucosal barrier in IBD is complex and only partly understood. There is no general agreement on how to define healed mucosa, but there is a general acceptance that clinicians should use endoscopy and imaging technique in their assessments. Mucosal healing is an old concept that has been actualized in the present era of the highly effective biological agents. Randomized clinical studies with mucosal healing as end-point parameters have been reported, and early mucosal healing has been associated with low complication rates. We are waiting for documentation of whether treatment to healed mucosa can change the natural course of IBD. The concept of immunological remission has recently been introduced and can be the new treatment goal and one of several criteria for discontinuation of biological treatment in IBD. In conclusion, mucosal healing is a fairly novel concept and goal for biological treatment of IBD. There is a need for a standardization of its assessment and validation of the prognostic value." @default.
- W1994720855 created "2016-06-24" @default.
- W1994720855 creator A5062560095 @default.
- W1994720855 date "2014-12-19" @default.
- W1994720855 modified "2023-09-25" @default.
- W1994720855 title "Mucosal healing in the era of biologic agents in treatment of inflammatory bowel disease" @default.
- W1994720855 cites W1562235336 @default.
- W1994720855 cites W1562899374 @default.
- W1994720855 cites W1900967856 @default.
- W1994720855 cites W1963625450 @default.
- W1994720855 cites W1964102710 @default.
- W1994720855 cites W1971685694 @default.
- W1994720855 cites W1974246098 @default.
- W1994720855 cites W1975911595 @default.
- W1994720855 cites W1978384449 @default.
- W1994720855 cites W1979178278 @default.
- W1994720855 cites W1991810959 @default.
- W1994720855 cites W1997350408 @default.
- W1994720855 cites W1999621861 @default.
- W1994720855 cites W2001775809 @default.
- W1994720855 cites W2006949775 @default.
- W1994720855 cites W2007196095 @default.
- W1994720855 cites W2008497900 @default.
- W1994720855 cites W2009028255 @default.
- W1994720855 cites W2009375421 @default.
- W1994720855 cites W2009410769 @default.
- W1994720855 cites W2016117582 @default.
- W1994720855 cites W2020350753 @default.
- W1994720855 cites W2022609044 @default.
- W1994720855 cites W2024121629 @default.
- W1994720855 cites W2024346860 @default.
- W1994720855 cites W2029723826 @default.
- W1994720855 cites W2031860350 @default.
- W1994720855 cites W2032473143 @default.
- W1994720855 cites W2039312624 @default.
- W1994720855 cites W2044963614 @default.
- W1994720855 cites W2047208232 @default.
- W1994720855 cites W2051252224 @default.
- W1994720855 cites W2052169347 @default.
- W1994720855 cites W2052474826 @default.
- W1994720855 cites W2053303708 @default.
- W1994720855 cites W2055222262 @default.
- W1994720855 cites W2055326611 @default.
- W1994720855 cites W2055582579 @default.
- W1994720855 cites W2056629400 @default.
- W1994720855 cites W2057141381 @default.
- W1994720855 cites W2059127937 @default.
- W1994720855 cites W2061048240 @default.
- W1994720855 cites W2061965920 @default.
- W1994720855 cites W2069756146 @default.
- W1994720855 cites W2071662837 @default.
- W1994720855 cites W2074916657 @default.
- W1994720855 cites W2076768379 @default.
- W1994720855 cites W2079332790 @default.
- W1994720855 cites W2081061562 @default.
- W1994720855 cites W2084262199 @default.
- W1994720855 cites W2087726829 @default.
- W1994720855 cites W2090685459 @default.
- W1994720855 cites W2092863985 @default.
- W1994720855 cites W2098295867 @default.
- W1994720855 cites W2100316531 @default.
- W1994720855 cites W2100338747 @default.
- W1994720855 cites W2102567329 @default.
- W1994720855 cites W2104892650 @default.
- W1994720855 cites W2121569640 @default.
- W1994720855 cites W2123571431 @default.
- W1994720855 cites W2123659088 @default.
- W1994720855 cites W2125533347 @default.
- W1994720855 cites W2126807394 @default.
- W1994720855 cites W2127478255 @default.
- W1994720855 cites W2127632431 @default.
- W1994720855 cites W2131027745 @default.
- W1994720855 cites W2135328294 @default.
- W1994720855 cites W2137647558 @default.
- W1994720855 cites W2145189896 @default.
- W1994720855 cites W2145436896 @default.
- W1994720855 cites W2150933705 @default.
- W1994720855 cites W2152381563 @default.
- W1994720855 cites W2152790886 @default.
- W1994720855 cites W2154052814 @default.
- W1994720855 cites W2160969462 @default.
- W1994720855 cites W2162766966 @default.
- W1994720855 cites W2162805528 @default.
- W1994720855 cites W2167806388 @default.
- W1994720855 cites W2168824301 @default.
- W1994720855 cites W2171297959 @default.
- W1994720855 cites W2171484002 @default.
- W1994720855 cites W2321205867 @default.
- W1994720855 cites W2321453230 @default.
- W1994720855 cites W2328917366 @default.
- W1994720855 cites W53419019 @default.
- W1994720855 doi "https://doi.org/10.3109/00365521.2014.977943" @default.
- W1994720855 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25523555" @default.
- W1994720855 hasPublicationYear "2014" @default.
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