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• W1994728684 abstract "The Fmoc/TAEA and Bsmoc/TAEA methods for the rapid, continuous solution synthesis of peptide segments are shown to be applicable to the gram-scale synthesis of short peptides as well as, for the first time, to the synthesis of a relatively long (22-mer) segment, (hPTH 13−34). In the latter case the crude product was of significantly greater purity than a sample obtained via a solid-phase protocol. The Bsmoc methodology was optimized by a new technique involving filtration of the growing partially deprotected peptide at each coupling−deprotection cycle through a short column of silica gel." @default.
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• W1994728684 date "2002-12-10" @default.
• W1994728684 modified "2023-10-17" @default.
• W1994728684 title "Rapid, Continuous Solution-Phase Peptide Synthesis: Application to Peptides of Pharmaceutical Interest" @default.
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• W1994728684 doi "https://doi.org/10.1021/op0202179" @default.
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