FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994827981> ?p ?o ?g. }

• W1994827981 endingPage "645" @default.
• W1994827981 startingPage "637" @default.
• W1994827981 abstract "We investigated the estrogenic activity of various environmental pollutants (xenobiotics), in particular the xenoestrogen o,p-DDT, and compared their effects with those of endogenous estrogens, phytoestrogens, and mycoestrogens on estrogen receptor binding capacity, induction of estrogen end products, and activation of cell proliferation in estrogen-sensitive human breast cancer cells in monolayer culture. We also quantified the levels of phytoestrogens in extracts of some common foods, herbs, and spices and in human saliva following consumption of a high phytoestrogen food source (soy milk) to compare phytoestrogen abundance and bioavailability relative to the reported xenoestrogen burden in humans. Results show that natural endogenous estrogens, phytoestrogens, mycoestrogens, and xenoestrogens bind estrogen receptor (ER) in intact cells, but demonstrate marked differences in their ability to induce end products of estrogen action and to regulate cell proliferation. All of the different classes of estrogens stimulated cell proliferation at concentrations that half-saturated ER, but only some classes were able to induce estrogen-regulated end products. Genistein, a common phytoestrogen found in soy foods, differed from the xenoestrogen DDT in its effects on cell proliferation and ability to induce estrogen-regulated end products. Moreover, we found that many of the foods, herbs, and spices commonly consumed by humans contain significant amounts of phytoestrogens, and consumption of soy milk, a phytoestrogen-rich food, markedly increases the levels of phytoestrogens in saliva. In conclusion, our in vitro results predict that a diet high in phytoestrogens would significantly reduce the binding of weak xenoestrogens to ER in target tissues in vivo." @default.
• W1994827981 created "2016-06-24" @default.
• W1994827981 creator A5052889227 @default.
• W1994827981 creator A5071703098 @default.
• W1994827981 creator A5083335938 @default.
• W1994827981 date "1997-04-01" @default.
• W1994827981 modified "2023-09-29" @default.
• W1994827981 title "Estrogenic activity of natural and synthetic estrogens in human breast cancer cells in culture." @default.
• W1994827981 cites W1535379194 @default.
• W1994827981 cites W1554095285 @default.
• W1994827981 cites W1677718874 @default.
• W1994827981 cites W1935548307 @default.
• W1994827981 cites W1964606698 @default.
• W1994827981 cites W1974172315 @default.
• W1994827981 cites W1981191061 @default.
• W1994827981 cites W1987050411 @default.
• W1994827981 cites W1989575465 @default.
• W1994827981 cites W1996947863 @default.
• W1994827981 cites W1999658218 @default.
• W1994827981 cites W2002021255 @default.
• W1994827981 cites W2007822731 @default.
• W1994827981 cites W2009040345 @default.
• W1994827981 cites W2009920039 @default.
• W1994827981 cites W2011725004 @default.
• W1994827981 cites W2014248078 @default.
• W1994827981 cites W2023704290 @default.
• W1994827981 cites W2026159928 @default.
• W1994827981 cites W2033558511 @default.
• W1994827981 cites W2039427523 @default.
• W1994827981 cites W2040664203 @default.
• W1994827981 cites W2041258563 @default.
• W1994827981 cites W2044653816 @default.
• W1994827981 cites W2047051281 @default.
• W1994827981 cites W2052322708 @default.
• W1994827981 cites W2061958057 @default.
• W1994827981 cites W2066347357 @default.
• W1994827981 cites W2068162251 @default.
• W1994827981 cites W2073264207 @default.
• W1994827981 cites W2074151102 @default.
• W1994827981 cites W2074826984 @default.
• W1994827981 cites W2086354507 @default.
• W1994827981 cites W2087022458 @default.
• W1994827981 cites W2106519485 @default.
• W1994827981 cites W2127451904 @default.
• W1994827981 cites W2137835163 @default.
• W1994827981 cites W2144551073 @default.
• W1994827981 cites W2154135601 @default.
• W1994827981 cites W2158944565 @default.
• W1994827981 cites W2170346923 @default.
• W1994827981 cites W2312911576 @default.
• W1994827981 cites W2312930460 @default.
• W1994827981 cites W2412930066 @default.
• W1994827981 doi "https://doi.org/10.1289/ehp.97105s3637" @default.
• W1994827981 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1469890" @default.
• W1994827981 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9168008" @default.
• W1994827981 hasPublicationYear "1997" @default.
• W1994827981 type Work @default.
• W1994827981 sameAs 1994827981 @default.
• W1994827981 citedByCount "91" @default.
• W1994827981 countsByYear W19948279812012 @default.
• W1994827981 countsByYear W19948279812013 @default.
• W1994827981 countsByYear W19948279812014 @default.
• W1994827981 countsByYear W19948279812015 @default.
• W1994827981 countsByYear W19948279812016 @default.
• W1994827981 countsByYear W19948279812017 @default.
• W1994827981 countsByYear W19948279812018 @default.
• W1994827981 countsByYear W19948279812019 @default.
• W1994827981 countsByYear W19948279812020 @default.
• W1994827981 countsByYear W19948279812021 @default.
• W1994827981 countsByYear W19948279812022 @default.
• W1994827981 crossrefType "journal-article" @default.
• W1994827981 hasAuthorship W1994827981A5052889227 @default.
• W1994827981 hasAuthorship W1994827981A5071703098 @default.
• W1994827981 hasAuthorship W1994827981A5083335938 @default.
• W1994827981 hasBestOaLocation W19948279811 @default.
• W1994827981 hasConcept C121608353 @default.
• W1994827981 hasConcept C126322002 @default.
• W1994827981 hasConcept C134018914 @default.
• W1994827981 hasConcept C16613235 @default.
• W1994827981 hasConcept C185592680 @default.
• W1994827981 hasConcept C2777164284 @default.
• W1994827981 hasConcept C2777927066 @default.
• W1994827981 hasConcept C2778270713 @default.
• W1994827981 hasConcept C2778298627 @default.
• W1994827981 hasConcept C2779272402 @default.
• W1994827981 hasConcept C2780955279 @default.
• W1994827981 hasConcept C2781262405 @default.
• W1994827981 hasConcept C530470458 @default.
• W1994827981 hasConcept C55493867 @default.
• W1994827981 hasConcept C62112901 @default.
• W1994827981 hasConcept C71924100 @default.
• W1994827981 hasConcept C84606932 @default.
• W1994827981 hasConcept C86803240 @default.
• W1994827981 hasConceptScore W1994827981C121608353 @default.
• W1994827981 hasConceptScore W1994827981C126322002 @default.
• W1994827981 hasConceptScore W1994827981C134018914 @default.
• W1994827981 hasConceptScore W1994827981C16613235 @default.
• W1994827981 hasConceptScore W1994827981C185592680 @default.

• next