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- W1994829897 abstract "Starting from a non-selective pyrazolo-pyrimidone lead, the sequential use of parallel medicinal chemistry and directed synthesis led to the discovery of potent, highly selective, and orally bioavailable PDE9 inhibitors. The availability of these tools allowed for a thorough evaluation of the therapeutic potential of PDE9 inhibition." @default.
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- W1994829897 date "2009-05-01" @default.
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- W1994829897 title "The discovery of potent, selective, and orally bioavailable PDE9 inhibitors as potential hypoglycemic agents" @default.
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- W1994829897 doi "https://doi.org/10.1016/j.bmcl.2009.03.024" @default.
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