Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994844412> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W1994844412 endingPage "1084" @default.
- W1994844412 startingPage "1077" @default.
- W1994844412 abstract "Background: Tissue engineering of patient-specific adipose tissue has the potential to revolutionize reconstructive surgery. Numerous models have been described for the production of adipose tissue with success in the short term, but little has been reported on the stability of this tissue-engineered fat beyond 4 months. Methods: A murine model of de novo adipogenesis producing a potentially transplantable adipose tissue flap within 4 to 6 weeks was developed in the authors’ laboratory. In this study, the authors assess the ability of three-chamber (44-μl volume) configurations shown to be adipogenic in previous short-term studies (autograft, n = 8; open, n = 6; fat flap, n = 11) to maintain their tissue volume for up to 12 months in vivo, to determine the most adipogenic configuration in the long term. Results: Those chambers having the most contact with existing vascularized adipose tissue (open and fat flap groups) showed increased mean adipose tissue percentage (77 ± 5.6 percent and 81 ± 6.9 percent, respectively; p < 0.0007) and volume (12 ± 6.8 μl and 30 ± 14 μl, respectively; p < 0.025) when compared with short-term controls and greater adipose tissue volume than the autograft (sealed) chamber group (4.9 ± 5.8 μl; p = 0.0001) at 1 year. Inclusion of a vascularized fat flap within the chamber produced the best results, with new fat completely filling the chamber by 1 year. Conclusions: These findings demonstrate that fat produced by tissue engineering is capable of maintaining its volume when the appropriate microenvironment is provided. This has important implications for the application of tissue-engineering techniques in humans." @default.
- W1994844412 created "2016-06-24" @default.
- W1994844412 creator A5029344208 @default.
- W1994844412 creator A5055874460 @default.
- W1994844412 creator A5060068121 @default.
- W1994844412 creator A5066353893 @default.
- W1994844412 date "2009-10-01" @default.
- W1994844412 modified "2023-10-16" @default.
- W1994844412 title "Long-Term Persistence of Tissue-Engineered Adipose Flaps in a Murine Model to 1 Year: An Update" @default.
- W1994844412 cites W1983430158 @default.
- W1994844412 cites W1983761772 @default.
- W1994844412 cites W1985527673 @default.
- W1994844412 cites W1990800923 @default.
- W1994844412 cites W1996911893 @default.
- W1994844412 cites W1999239339 @default.
- W1994844412 cites W2005794950 @default.
- W1994844412 cites W2010310262 @default.
- W1994844412 cites W2011709603 @default.
- W1994844412 cites W2014364740 @default.
- W1994844412 cites W2015648732 @default.
- W1994844412 cites W2019557424 @default.
- W1994844412 cites W2031808035 @default.
- W1994844412 cites W2041925658 @default.
- W1994844412 cites W2067093043 @default.
- W1994844412 cites W2070300141 @default.
- W1994844412 cites W2084245009 @default.
- W1994844412 cites W2087848673 @default.
- W1994844412 cites W2152215024 @default.
- W1994844412 cites W2232720540 @default.
- W1994844412 doi "https://doi.org/10.1097/prs.0b013e3181b59ff6" @default.
- W1994844412 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19935290" @default.
- W1994844412 hasPublicationYear "2009" @default.
- W1994844412 type Work @default.
- W1994844412 sameAs 1994844412 @default.
- W1994844412 citedByCount "24" @default.
- W1994844412 countsByYear W19948444122012 @default.
- W1994844412 countsByYear W19948444122013 @default.
- W1994844412 countsByYear W19948444122014 @default.
- W1994844412 countsByYear W19948444122016 @default.
- W1994844412 countsByYear W19948444122017 @default.
- W1994844412 countsByYear W19948444122018 @default.
- W1994844412 countsByYear W19948444122019 @default.
- W1994844412 countsByYear W19948444122020 @default.
- W1994844412 countsByYear W19948444122021 @default.
- W1994844412 countsByYear W19948444122022 @default.
- W1994844412 crossrefType "journal-article" @default.
- W1994844412 hasAuthorship W1994844412A5029344208 @default.
- W1994844412 hasAuthorship W1994844412A5055874460 @default.
- W1994844412 hasAuthorship W1994844412A5060068121 @default.
- W1994844412 hasAuthorship W1994844412A5066353893 @default.
- W1994844412 hasConcept C121332964 @default.
- W1994844412 hasConcept C122927707 @default.
- W1994844412 hasConcept C126322002 @default.
- W1994844412 hasConcept C136229726 @default.
- W1994844412 hasConcept C141071460 @default.
- W1994844412 hasConcept C150903083 @default.
- W1994844412 hasConcept C171089720 @default.
- W1994844412 hasConcept C20556612 @default.
- W1994844412 hasConcept C207001950 @default.
- W1994844412 hasConcept C49892992 @default.
- W1994844412 hasConcept C62520636 @default.
- W1994844412 hasConcept C71924100 @default.
- W1994844412 hasConcept C86803240 @default.
- W1994844412 hasConceptScore W1994844412C121332964 @default.
- W1994844412 hasConceptScore W1994844412C122927707 @default.
- W1994844412 hasConceptScore W1994844412C126322002 @default.
- W1994844412 hasConceptScore W1994844412C136229726 @default.
- W1994844412 hasConceptScore W1994844412C141071460 @default.
- W1994844412 hasConceptScore W1994844412C150903083 @default.
- W1994844412 hasConceptScore W1994844412C171089720 @default.
- W1994844412 hasConceptScore W1994844412C20556612 @default.
- W1994844412 hasConceptScore W1994844412C207001950 @default.
- W1994844412 hasConceptScore W1994844412C49892992 @default.
- W1994844412 hasConceptScore W1994844412C62520636 @default.
- W1994844412 hasConceptScore W1994844412C71924100 @default.
- W1994844412 hasConceptScore W1994844412C86803240 @default.
- W1994844412 hasIssue "4" @default.
- W1994844412 hasLocation W19948444121 @default.
- W1994844412 hasOpenAccess W1994844412 @default.
- W1994844412 hasPrimaryLocation W19948444121 @default.
- W1994844412 hasRelatedWork W1574287054 @default.
- W1994844412 hasRelatedWork W1992403567 @default.
- W1994844412 hasRelatedWork W2028744988 @default.
- W1994844412 hasRelatedWork W2048604637 @default.
- W1994844412 hasRelatedWork W2084245009 @default.
- W1994844412 hasRelatedWork W2147410376 @default.
- W1994844412 hasRelatedWork W2159546193 @default.
- W1994844412 hasRelatedWork W3032399641 @default.
- W1994844412 hasRelatedWork W4308142614 @default.
- W1994844412 hasRelatedWork W4318941303 @default.
- W1994844412 hasVolume "124" @default.
- W1994844412 isParatext "false" @default.
- W1994844412 isRetracted "false" @default.
- W1994844412 magId "1994844412" @default.
- W1994844412 workType "article" @default.