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- W1994853513 abstract "The canonical role of p53 in preserving genome integrity and limiting carcinogenesis has been well established. In the presence of acute DNA-damage, oncogene deregulation and other forms of cellular stress, p53 orchestrates a myriad of pleiotropic processes to repair cellular damages and maintain homeostasis. Beside these well-studied functions of p53, recent studies in Drosophila have unraveled intriguing roles of Dmp53 in promoting cell division in apoptosis-induced proliferation, enhancing fitness and proliferation of the winner cell in cell competition and coordinating growth at the organ and organismal level in the presence of stress. In this review, we describe these new functions of Dmp53 and discuss their relevance in the context of carcinogenesis." @default.
- W1994853513 created "2016-06-24" @default.
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- W1994853513 date "2014-09-13" @default.
- W1994853513 modified "2023-09-25" @default.
- W1994853513 title "The p53 control of apoptosis and proliferation: lessons from Drosophila" @default.
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- W1994853513 doi "https://doi.org/10.1007/s10495-014-1035-7" @default.
- W1994853513 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4167030" @default.
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