Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994886735> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1994886735 endingPage "2518" @default.
- W1994886735 startingPage "2495" @default.
- W1994886735 abstract "AbstractAbstractThe main purpose of this investigation was to evaluate ethylcellulose as a carrier for the preparation of prolonged release solid dispersions of sparingly water-soluble drugs, ibuprofen and indomethacin. Solid dispersions containing various concentrations of ethylcellulose of different viscosity grades were prepared by the solvent method. Tablets were directly compressed from solid dispersions (40/100 mesh) with 0.5% Primojel as a disintegrant and 0.5% magnesium stearate as a lubricant. In vitro release studies employed a rotating bottle system with Sorenson's buffer solution (pH 7.4). It was found that prolongation of drug release was primarily associated with an increase in amount of ethylcellulose rather than the viscosity grade. Nonetheless, the higher the viscosity grade of ethylcellulose, the slower the release of drug from granular and compressed solid dispersions. The release rate of ibuprofen was faster than that of indomethacin from different solid dispersion formulations." @default.
- W1994886735 created "2016-06-24" @default.
- W1994886735 creator A5059844701 @default.
- W1994886735 creator A5078157069 @default.
- W1994886735 creator A5086493666 @default.
- W1994886735 date "1987-01-01" @default.
- W1994886735 modified "2023-10-10" @default.
- W1994886735 title "Evaluation of Ethylcellulose as a Matrix for Prolonged Release Formulations. II. Sparingly Water-Soluble Drugs: Ibuprofen and Indomethacin" @default.
- W1994886735 cites W1982962177 @default.
- W1994886735 cites W1983156092 @default.
- W1994886735 cites W1983473009 @default.
- W1994886735 cites W1989816837 @default.
- W1994886735 cites W2032899843 @default.
- W1994886735 cites W2033710888 @default.
- W1994886735 cites W2040432233 @default.
- W1994886735 cites W2051556368 @default.
- W1994886735 cites W2071292129 @default.
- W1994886735 cites W2072591130 @default.
- W1994886735 cites W2086130473 @default.
- W1994886735 cites W2110789325 @default.
- W1994886735 cites W2146445795 @default.
- W1994886735 cites W2156580034 @default.
- W1994886735 cites W4298213231 @default.
- W1994886735 doi "https://doi.org/10.3109/03639048709020600" @default.
- W1994886735 hasPublicationYear "1987" @default.
- W1994886735 type Work @default.
- W1994886735 sameAs 1994886735 @default.
- W1994886735 citedByCount "27" @default.
- W1994886735 countsByYear W19948867352014 @default.
- W1994886735 countsByYear W19948867352015 @default.
- W1994886735 countsByYear W19948867352019 @default.
- W1994886735 crossrefType "journal-article" @default.
- W1994886735 hasAuthorship W1994886735A5059844701 @default.
- W1994886735 hasAuthorship W1994886735A5078157069 @default.
- W1994886735 hasAuthorship W1994886735A5086493666 @default.
- W1994886735 hasConcept C127172972 @default.
- W1994886735 hasConcept C159985019 @default.
- W1994886735 hasConcept C178790620 @default.
- W1994886735 hasConcept C185592680 @default.
- W1994886735 hasConcept C192562407 @default.
- W1994886735 hasConcept C202751555 @default.
- W1994886735 hasConcept C2776711897 @default.
- W1994886735 hasConcept C2777239854 @default.
- W1994886735 hasConcept C2778572730 @default.
- W1994886735 hasConcept C2779671005 @default.
- W1994886735 hasConcept C2779944601 @default.
- W1994886735 hasConcept C2780471494 @default.
- W1994886735 hasConcept C2780874159 @default.
- W1994886735 hasConcept C43617362 @default.
- W1994886735 hasConcept C55493867 @default.
- W1994886735 hasConcept C71924100 @default.
- W1994886735 hasConcept C77281830 @default.
- W1994886735 hasConcept C98274493 @default.
- W1994886735 hasConceptScore W1994886735C127172972 @default.
- W1994886735 hasConceptScore W1994886735C159985019 @default.
- W1994886735 hasConceptScore W1994886735C178790620 @default.
- W1994886735 hasConceptScore W1994886735C185592680 @default.
- W1994886735 hasConceptScore W1994886735C192562407 @default.
- W1994886735 hasConceptScore W1994886735C202751555 @default.
- W1994886735 hasConceptScore W1994886735C2776711897 @default.
- W1994886735 hasConceptScore W1994886735C2777239854 @default.
- W1994886735 hasConceptScore W1994886735C2778572730 @default.
- W1994886735 hasConceptScore W1994886735C2779671005 @default.
- W1994886735 hasConceptScore W1994886735C2779944601 @default.
- W1994886735 hasConceptScore W1994886735C2780471494 @default.
- W1994886735 hasConceptScore W1994886735C2780874159 @default.
- W1994886735 hasConceptScore W1994886735C43617362 @default.
- W1994886735 hasConceptScore W1994886735C55493867 @default.
- W1994886735 hasConceptScore W1994886735C71924100 @default.
- W1994886735 hasConceptScore W1994886735C77281830 @default.
- W1994886735 hasConceptScore W1994886735C98274493 @default.
- W1994886735 hasIssue "14" @default.
- W1994886735 hasLocation W19948867351 @default.
- W1994886735 hasOpenAccess W1994886735 @default.
- W1994886735 hasPrimaryLocation W19948867351 @default.
- W1994886735 hasRelatedWork W1968102018 @default.
- W1994886735 hasRelatedWork W1985653410 @default.
- W1994886735 hasRelatedWork W2003427276 @default.
- W1994886735 hasRelatedWork W2031730243 @default.
- W1994886735 hasRelatedWork W2052280371 @default.
- W1994886735 hasRelatedWork W2073156916 @default.
- W1994886735 hasRelatedWork W2288372844 @default.
- W1994886735 hasRelatedWork W2413673256 @default.
- W1994886735 hasRelatedWork W3071595245 @default.
- W1994886735 hasRelatedWork W3130176031 @default.
- W1994886735 hasVolume "13" @default.
- W1994886735 isParatext "false" @default.
- W1994886735 isRetracted "false" @default.
- W1994886735 magId "1994886735" @default.
- W1994886735 workType "article" @default.