Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994888570> ?p ?o ?g. }
- W1994888570 endingPage "1187" @default.
- W1994888570 startingPage "1178" @default.
- W1994888570 abstract "The effect of doxazosin versus captopril on blood pressure, albuminuria, and left ventricular mass was studied in 33 hypertensive type-1 diabetic patients randomized to 6 months treatment with captopril (17 patients, mean daily dose 100 mg) or doxazosin (16 patients, mean daily dose 9 mg). Casual and 24-h ambulatory blood pressure (24hBP) were reduced from 163/95 to 144/83 mm Hg and 152/86 to 145/81 mm Hg, respectively, in the captopril group, and from 160/93 to 145/86 mm Hg and 156/86 to 147/79 mm Hg in the doxazosin group (all P < .05). The achieved 24hBP on treatment was positively associated with pretreatment levels of glycosylated hemoglobin (HbA1c) and plasma atrial natriuretic peptide (r = 0.53 and 0.59, respectively, both P < .01). Albuminuria did not change significantly in either group. Left ventricular hypertrophy was present in 13 patients (7 in the captopril and 6 in the doxazosin group). Left ventricular mass was reduced by an average of 27% and 23%, respectively, in these patients (both P < .01), but did not change significantly in patients without left ventricular hypertrophy. The reduction in left ventricular mass was positively associated with the presence of baseline left ventricular hypertrophy and inversely with dietary sodium intake and achieved casual blood pressure on treatment (R2 = 0.59, P < .001). We conclude that doxazosin and captopril used for 6 months are equally effective in reducing blood pressure and left ventricular hypertrophy in hypertensive type-1 diabetic patients; the antihypertensive effect is closely related to glycemic control; and dietary sodium intake and achieved casual blood pressure after treatment are independent determinants of the reduction in left ventricular mass seen in these patients. Am J Hypertens 1998;11:1178–1187 © 1998 American Journal of Hypertension, Ltd." @default.
- W1994888570 created "2016-06-24" @default.
- W1994888570 creator A5000248384 @default.
- W1994888570 creator A5007326335 @default.
- W1994888570 creator A5030715474 @default.
- W1994888570 creator A5034871954 @default.
- W1994888570 creator A5038806566 @default.
- W1994888570 creator A5090567122 @default.
- W1994888570 date "1998-10-01" @default.
- W1994888570 modified "2023-09-25" @default.
- W1994888570 title "Factors influencing reduction in blood pressure and left ventricular mass in hypertensive type-1 diabetic patients using captopril or doxazosin for 6 months☆" @default.
- W1994888570 cites W138877151 @default.
- W1994888570 cites W1480131382 @default.
- W1994888570 cites W1509696066 @default.
- W1994888570 cites W1769893219 @default.
- W1994888570 cites W1963878069 @default.
- W1994888570 cites W1966076727 @default.
- W1994888570 cites W1976069713 @default.
- W1994888570 cites W1976111715 @default.
- W1994888570 cites W1982079739 @default.
- W1994888570 cites W1983574826 @default.
- W1994888570 cites W1985957699 @default.
- W1994888570 cites W1999218740 @default.
- W1994888570 cites W2005124311 @default.
- W1994888570 cites W2007098380 @default.
- W1994888570 cites W2015146823 @default.
- W1994888570 cites W2022264052 @default.
- W1994888570 cites W2034675050 @default.
- W1994888570 cites W2041432237 @default.
- W1994888570 cites W2042293234 @default.
- W1994888570 cites W2043054513 @default.
- W1994888570 cites W2045261889 @default.
- W1994888570 cites W2052834432 @default.
- W1994888570 cites W2057520114 @default.
- W1994888570 cites W2063732928 @default.
- W1994888570 cites W2080950711 @default.
- W1994888570 cites W2082608636 @default.
- W1994888570 cites W2086987747 @default.
- W1994888570 cites W2096073058 @default.
- W1994888570 cites W2096458831 @default.
- W1994888570 cites W2101711790 @default.
- W1994888570 cites W2108337833 @default.
- W1994888570 cites W2116545635 @default.
- W1994888570 cites W2136729811 @default.
- W1994888570 cites W2154813402 @default.
- W1994888570 cites W2171022041 @default.
- W1994888570 cites W2319911420 @default.
- W1994888570 cites W2334558441 @default.
- W1994888570 cites W2338938416 @default.
- W1994888570 cites W2403786754 @default.
- W1994888570 cites W2410567973 @default.
- W1994888570 cites W2468923226 @default.
- W1994888570 cites W2475021297 @default.
- W1994888570 cites W2566199751 @default.
- W1994888570 cites W2626172039 @default.
- W1994888570 cites W2769264260 @default.
- W1994888570 cites W3012166899 @default.
- W1994888570 cites W2145160336 @default.
- W1994888570 cites W2401908002 @default.
- W1994888570 doi "https://doi.org/10.1016/s0895-7061(98)00194-0" @default.
- W1994888570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9799034" @default.
- W1994888570 hasPublicationYear "1998" @default.
- W1994888570 type Work @default.
- W1994888570 sameAs 1994888570 @default.
- W1994888570 citedByCount "9" @default.
- W1994888570 countsByYear W19948885702013 @default.
- W1994888570 crossrefType "journal-article" @default.
- W1994888570 hasAuthorship W1994888570A5000248384 @default.
- W1994888570 hasAuthorship W1994888570A5007326335 @default.
- W1994888570 hasAuthorship W1994888570A5030715474 @default.
- W1994888570 hasAuthorship W1994888570A5034871954 @default.
- W1994888570 hasAuthorship W1994888570A5038806566 @default.
- W1994888570 hasAuthorship W1994888570A5090567122 @default.
- W1994888570 hasBestOaLocation W19948885701 @default.
- W1994888570 hasConcept C126322002 @default.
- W1994888570 hasConcept C134018914 @default.
- W1994888570 hasConcept C149323552 @default.
- W1994888570 hasConcept C164705383 @default.
- W1994888570 hasConcept C167414201 @default.
- W1994888570 hasConcept C27016395 @default.
- W1994888570 hasConcept C2776002628 @default.
- W1994888570 hasConcept C2777097880 @default.
- W1994888570 hasConcept C2777590997 @default.
- W1994888570 hasConcept C2777953023 @default.
- W1994888570 hasConcept C2779479957 @default.
- W1994888570 hasConcept C2779611605 @default.
- W1994888570 hasConcept C2992203999 @default.
- W1994888570 hasConcept C71924100 @default.
- W1994888570 hasConcept C84393581 @default.
- W1994888570 hasConceptScore W1994888570C126322002 @default.
- W1994888570 hasConceptScore W1994888570C134018914 @default.
- W1994888570 hasConceptScore W1994888570C149323552 @default.
- W1994888570 hasConceptScore W1994888570C164705383 @default.
- W1994888570 hasConceptScore W1994888570C167414201 @default.
- W1994888570 hasConceptScore W1994888570C27016395 @default.
- W1994888570 hasConceptScore W1994888570C2776002628 @default.
- W1994888570 hasConceptScore W1994888570C2777097880 @default.
- W1994888570 hasConceptScore W1994888570C2777590997 @default.