Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994889035> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W1994889035 endingPage "119" @default.
- W1994889035 startingPage "115" @default.
- W1994889035 abstract "Ninety patients with salivary gland or squamous cell tumours of the head and neck region presenting to two centres were included in a double blind controlled clinical trial of radiation plus razoxane versus radiation plus placebo. The patients were paired according to treatment centre, sex, tumour site and tumour stage, one member of a pair receiving razoxane and one placebo during radiotherapy. The dose of razoxane administered was 125 mg in the morning and 62.5 mg in the evening of each day of radiation. The treatments were assessed by comparing the tumour response of pairs of patients and the preferences for treatment type analyzed sequentially on the plan described by Bross. Of the 18 pairs eligible for analysis at the completion of the trial, one showed a preference for the treatment radiation plus razoxane, nine for the treatment radiation plus placebo, four showed no preference for either treatment and four had not been assessed. The conclusion drawn from the sequential analysis of the results is that razoxane, in the dose and schedule employed, has a deleterious effect on the response of head and neck tumours to radiation. Excluding a positive placebo action, the possibility of a radioprotective effect of razoxane is discussed and the importance of reconsidering the dose and timing of administration of the drug in future clinical studies is emphasized." @default.
- W1994889035 created "2016-06-24" @default.
- W1994889035 creator A5011375041 @default.
- W1994889035 creator A5015142352 @default.
- W1994889035 creator A5016798636 @default.
- W1994889035 creator A5020590390 @default.
- W1994889035 creator A5028064074 @default.
- W1994889035 creator A5054326949 @default.
- W1994889035 creator A5055286811 @default.
- W1994889035 creator A5057235819 @default.
- W1994889035 creator A5071662506 @default.
- W1994889035 creator A5075854480 @default.
- W1994889035 creator A5079614707 @default.
- W1994889035 date "1978-01-01" @default.
- W1994889035 modified "2023-09-27" @default.
- W1994889035 title "Double blind controlled clinical trial of radiation plus razoxane (ICRF 159) versus radiation plus placebo in the treatment of head and neck cancer" @default.
- W1994889035 cites W1968298721 @default.
- W1994889035 cites W1985850151 @default.
- W1994889035 cites W2041055782 @default.
- W1994889035 cites W2080526182 @default.
- W1994889035 cites W2138329937 @default.
- W1994889035 cites W2329126122 @default.
- W1994889035 cites W252692730 @default.
- W1994889035 doi "https://doi.org/10.1016/0360-3016(78)90125-6" @default.
- W1994889035 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/344287" @default.
- W1994889035 hasPublicationYear "1978" @default.
- W1994889035 type Work @default.
- W1994889035 sameAs 1994889035 @default.
- W1994889035 citedByCount "19" @default.
- W1994889035 countsByYear W19948890352017 @default.
- W1994889035 countsByYear W19948890352021 @default.
- W1994889035 crossrefType "journal-article" @default.
- W1994889035 hasAuthorship W1994889035A5011375041 @default.
- W1994889035 hasAuthorship W1994889035A5015142352 @default.
- W1994889035 hasAuthorship W1994889035A5016798636 @default.
- W1994889035 hasAuthorship W1994889035A5020590390 @default.
- W1994889035 hasAuthorship W1994889035A5028064074 @default.
- W1994889035 hasAuthorship W1994889035A5054326949 @default.
- W1994889035 hasAuthorship W1994889035A5055286811 @default.
- W1994889035 hasAuthorship W1994889035A5057235819 @default.
- W1994889035 hasAuthorship W1994889035A5071662506 @default.
- W1994889035 hasAuthorship W1994889035A5075854480 @default.
- W1994889035 hasAuthorship W1994889035A5079614707 @default.
- W1994889035 hasConcept C126322002 @default.
- W1994889035 hasConcept C141071460 @default.
- W1994889035 hasConcept C142724271 @default.
- W1994889035 hasConcept C143998085 @default.
- W1994889035 hasConcept C204787440 @default.
- W1994889035 hasConcept C27081682 @default.
- W1994889035 hasConcept C2776530083 @default.
- W1994889035 hasConcept C2991744798 @default.
- W1994889035 hasConcept C509974204 @default.
- W1994889035 hasConcept C535046627 @default.
- W1994889035 hasConcept C71924100 @default.
- W1994889035 hasConceptScore W1994889035C126322002 @default.
- W1994889035 hasConceptScore W1994889035C141071460 @default.
- W1994889035 hasConceptScore W1994889035C142724271 @default.
- W1994889035 hasConceptScore W1994889035C143998085 @default.
- W1994889035 hasConceptScore W1994889035C204787440 @default.
- W1994889035 hasConceptScore W1994889035C27081682 @default.
- W1994889035 hasConceptScore W1994889035C2776530083 @default.
- W1994889035 hasConceptScore W1994889035C2991744798 @default.
- W1994889035 hasConceptScore W1994889035C509974204 @default.
- W1994889035 hasConceptScore W1994889035C535046627 @default.
- W1994889035 hasConceptScore W1994889035C71924100 @default.
- W1994889035 hasIssue "1-2" @default.
- W1994889035 hasLocation W19948890351 @default.
- W1994889035 hasLocation W19948890352 @default.
- W1994889035 hasOpenAccess W1994889035 @default.
- W1994889035 hasPrimaryLocation W19948890351 @default.
- W1994889035 hasRelatedWork W1972442584 @default.
- W1994889035 hasRelatedWork W2079484102 @default.
- W1994889035 hasRelatedWork W2086793060 @default.
- W1994889035 hasRelatedWork W2110125130 @default.
- W1994889035 hasRelatedWork W2129428300 @default.
- W1994889035 hasRelatedWork W2434030757 @default.
- W1994889035 hasRelatedWork W3122076712 @default.
- W1994889035 hasRelatedWork W4212922089 @default.
- W1994889035 hasRelatedWork W4235542796 @default.
- W1994889035 hasRelatedWork W4361015616 @default.
- W1994889035 hasVolume "4" @default.
- W1994889035 isParatext "false" @default.
- W1994889035 isRetracted "false" @default.
- W1994889035 magId "1994889035" @default.
- W1994889035 workType "article" @default.