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- W1994911220 abstract "Heat shock protein 90 (Hsp90) is an attractive cancer target that possesses two potential binding domains at the C and N termini. Nevertheless, assays that can reliably distinguish between the C- and N-terminal Hsp90 inhibitors and quantitatively characterize candidate drugs are limited. Here we report an Hsp90 binding assay and ATPase inhibition assay that can not only separate the C- and N-terminal inhibitors but also quantitatively determine their respective IC50 values." @default.
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- W1994911220 date "2013-07-01" @default.
- W1994911220 modified "2023-09-27" @default.
- W1994911220 title "Functional characterization of heat shock protein 90 targeted compounds" @default.
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- W1994911220 doi "https://doi.org/10.1016/j.ab.2013.03.026" @default.
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