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- W1994927206 abstract "N-formyl-L-methionine is rapidly hydrolyzed by homogenates and cytosol fractions of rat tissues and of chicken liver, beef brain and pig kidney. Other N-formyl aminoacids are not, or are hydrolyzed at much slower rates. The cytosol fractions may be dialyzed, and their activity is not affected by Mn++, Mg++ and Co++. The optimum pH is about 7.4. The KM varies from 3 to 12 mM with different rat tissues, i.e. of the same order as that of the deformylase from Euglena gracilis (3.8 mM). The N-formyl-methionine deformylase of animal tissues may represent a hitherto unrecognized activity of the previously described aminoacylases. This and possible physiological role(s) are discussed." @default.
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- W1994927206 date "1977-07-01" @default.
- W1994927206 modified "2023-09-25" @default.
- W1994927206 title "N-formyl-methionine deformylase of animal tissues" @default.
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- W1994927206 doi "https://doi.org/10.1016/s0006-291x(77)80188-5" @default.
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