Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994929042> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W1994929042 endingPage "410" @default.
- W1994929042 startingPage "407" @default.
- W1994929042 abstract "To determine postnatal changes in neonatal serum concentrations of interferon-gamma (IFN-gamma), interleukin-4 (IL-4) and its soluble receptor (sIL-4R).Forty-five healthy term neonates, 25 of the neonates' mothers and 27 healthy adults (controls) participated in the study. Cytokine concentrations were measured in blood samples from the umbilical cord, from the neonates on the 1st and 5th day after birth, from mothers and from controls.IFN-gamma concentrations were significantly lower in the umbilical cord, compared to concentrations in the controls (p < 0.04), and increased significantly from the umbilical cord to levels in neonates on day 5 (p < 0.03). In mothers and the umbilical cord, IFN-gamma concentrations were dependent on the mode of delivery, being higher after vaginal delivery than after elective Cesarean section (p < 0.005; p < 0.006, respectively). IL-4 concentrations in the umbilical cord for 1-day and 5-day neonates were significantly elevated compared to those in mothers (p < 0.001; p < 0.0007; p < 0.0001, respectively) and controls (p < 0.05; p < 0.01; p < 0.006, respectively). sIL-4R concentrations in all neonatal samples were significantly elevated compared to those in controls (p < 0.0001), the highest being found in 1-day-old neonates. A strong negative correlation was found between IL-4 and sIL-4R concentrations in 1- and 5-day-old neonates (r = -0.48, p < 0.002; r = -0.45, p < 0.0065, respectively). Moreover, IFN-gamma/IL-4 ratio increased significantly from the umbilical cord to 5 days of life (p < 0.03).Our findings indicate an earlier development of IL-4 than IFN-gamma, which could be viewed as a developmental characteristic in the ontogeny of the immune system." @default.
- W1994929042 created "2016-06-24" @default.
- W1994929042 creator A5013064311 @default.
- W1994929042 creator A5052279351 @default.
- W1994929042 creator A5061067052 @default.
- W1994929042 creator A5066221325 @default.
- W1994929042 creator A5090657757 @default.
- W1994929042 creator A5090777994 @default.
- W1994929042 date "2003-01-01" @default.
- W1994929042 modified "2023-09-27" @default.
- W1994929042 title "Alterations in Th1/Th2 cytokine concentrations in early neonatal life" @default.
- W1994929042 cites W1534923950 @default.
- W1994929042 cites W2009539256 @default.
- W1994929042 cites W2019995497 @default.
- W1994929042 cites W2052683965 @default.
- W1994929042 doi "https://doi.org/10.1080/14767050412331312270" @default.
- W1994929042 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15061321" @default.
- W1994929042 hasPublicationYear "2003" @default.
- W1994929042 type Work @default.
- W1994929042 sameAs 1994929042 @default.
- W1994929042 citedByCount "20" @default.
- W1994929042 countsByYear W19949290422014 @default.
- W1994929042 countsByYear W19949290422022 @default.
- W1994929042 crossrefType "journal-article" @default.
- W1994929042 hasAuthorship W1994929042A5013064311 @default.
- W1994929042 hasAuthorship W1994929042A5052279351 @default.
- W1994929042 hasAuthorship W1994929042A5061067052 @default.
- W1994929042 hasAuthorship W1994929042A5066221325 @default.
- W1994929042 hasAuthorship W1994929042A5090657757 @default.
- W1994929042 hasAuthorship W1994929042A5090777994 @default.
- W1994929042 hasConcept C126322002 @default.
- W1994929042 hasConcept C134018914 @default.
- W1994929042 hasConcept C141071460 @default.
- W1994929042 hasConcept C203014093 @default.
- W1994929042 hasConcept C2776955114 @default.
- W1994929042 hasConcept C2778408130 @default.
- W1994929042 hasConcept C2778690821 @default.
- W1994929042 hasConcept C2779234561 @default.
- W1994929042 hasConcept C2779632786 @default.
- W1994929042 hasConcept C2780914630 @default.
- W1994929042 hasConcept C2909718597 @default.
- W1994929042 hasConcept C54355233 @default.
- W1994929042 hasConcept C71924100 @default.
- W1994929042 hasConcept C86803240 @default.
- W1994929042 hasConceptScore W1994929042C126322002 @default.
- W1994929042 hasConceptScore W1994929042C134018914 @default.
- W1994929042 hasConceptScore W1994929042C141071460 @default.
- W1994929042 hasConceptScore W1994929042C203014093 @default.
- W1994929042 hasConceptScore W1994929042C2776955114 @default.
- W1994929042 hasConceptScore W1994929042C2778408130 @default.
- W1994929042 hasConceptScore W1994929042C2778690821 @default.
- W1994929042 hasConceptScore W1994929042C2779234561 @default.
- W1994929042 hasConceptScore W1994929042C2779632786 @default.
- W1994929042 hasConceptScore W1994929042C2780914630 @default.
- W1994929042 hasConceptScore W1994929042C2909718597 @default.
- W1994929042 hasConceptScore W1994929042C54355233 @default.
- W1994929042 hasConceptScore W1994929042C71924100 @default.
- W1994929042 hasConceptScore W1994929042C86803240 @default.
- W1994929042 hasIssue "6" @default.
- W1994929042 hasLocation W19949290421 @default.
- W1994929042 hasLocation W19949290422 @default.
- W1994929042 hasOpenAccess W1994929042 @default.
- W1994929042 hasPrimaryLocation W19949290421 @default.
- W1994929042 hasRelatedWork W1224776244 @default.
- W1994929042 hasRelatedWork W1984967362 @default.
- W1994929042 hasRelatedWork W1987142704 @default.
- W1994929042 hasRelatedWork W1994929042 @default.
- W1994929042 hasRelatedWork W1997881520 @default.
- W1994929042 hasRelatedWork W2004252040 @default.
- W1994929042 hasRelatedWork W2139614005 @default.
- W1994929042 hasRelatedWork W2248492076 @default.
- W1994929042 hasRelatedWork W2315598298 @default.
- W1994929042 hasRelatedWork W2598114161 @default.
- W1994929042 hasVolume "14" @default.
- W1994929042 isParatext "false" @default.
- W1994929042 isRetracted "false" @default.
- W1994929042 magId "1994929042" @default.
- W1994929042 workType "article" @default.