FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994967425> ?p ?o ?g. }

• W1994967425 endingPage "142" @default.
• W1994967425 startingPage "137" @default.
• W1994967425 abstract "Sickle cell anemia (SCA) is an inherited disorder of hemoglobin synthesis that is characterized by life-long severe hemolytic anemia, attacks of pain crisis, and chronic organ system damage. In this study, prenatal diagnosis was performed to three couples (families A, B, and C) with twin pregnancies who were at risk for SCA.The SCA carrier state of the couples were confirmed at molecular level. Chorionic villus samples (CVS) of twins were obtained at 10-12 weeks of gestation. Amplification refractory mutation system (ARMS) and restriction fragment length polymorphism (RFLP) techniques were applied to determine and confirm the presence of the sickle cell anemia of the fetuses. Identification of each twin, confirmation of parentage and elimination of maternal contamination of chorionic villus samples were ruled out by variable number of tandem repeats (VNTR) analysis of four different loci [D1S80 (pMCT118), ApoB, IgJH, D4S95].We found that one of the fetuses was heterozygous for SCA and the other was normal in family A; in family B both fetuses were heterozygous and in family C both fetuses were normal.Prenatal diagnosis is the major way of prevention of the genetic disorders including sickle cell anemia. Prenatal diagnosis of twins contains additional risks such as confusion in differentiation leading to false molecular diagnosis. VNTR loci analysis is a useful tool and can be safely used for the elimination of all problems mentioned above." @default.
• W1994967425 created "2016-06-24" @default.
• W1994967425 creator A5005571140 @default.
• W1994967425 creator A5008220682 @default.
• W1994967425 creator A5014431486 @default.
• W1994967425 creator A5026955178 @default.
• W1994967425 creator A5033979189 @default.
• W1994967425 date "2004-12-01" @default.
• W1994967425 modified "2023-10-03" @default.
• W1994967425 title "Prenatal diagnosis of sickle cell anemia in twin pregnancies and identification by VNTRs" @default.
• W1994967425 cites W136157357 @default.
• W1994967425 cites W1992537876 @default.
• W1994967425 cites W1993106337 @default.
• W1994967425 cites W2000443425 @default.
• W1994967425 cites W2006463895 @default.
• W1994967425 cites W2017993118 @default.
• W1994967425 cites W2019580959 @default.
• W1994967425 cites W2022327743 @default.
• W1994967425 cites W2032272243 @default.
• W1994967425 cites W2040855912 @default.
• W1994967425 cites W2050717506 @default.
• W1994967425 cites W2064063117 @default.
• W1994967425 cites W2080726106 @default.
• W1994967425 cites W2082416830 @default.
• W1994967425 cites W2087184465 @default.
• W1994967425 cites W2102239131 @default.
• W1994967425 cites W2131867446 @default.
• W1994967425 cites W2171951934 @default.
• W1994967425 cites W23225616 @default.
• W1994967425 cites W2326476344 @default.
• W1994967425 cites W4251413234 @default.
• W1994967425 cites W84802023 @default.
• W1994967425 doi "https://doi.org/10.1016/j.cccn.2004.07.020" @default.
• W1994967425 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15530470" @default.
• W1994967425 hasPublicationYear "2004" @default.
• W1994967425 type Work @default.
• W1994967425 sameAs 1994967425 @default.
• W1994967425 citedByCount "11" @default.
• W1994967425 countsByYear W19949674252012 @default.
• W1994967425 countsByYear W19949674252013 @default.
• W1994967425 countsByYear W19949674252014 @default.
• W1994967425 countsByYear W19949674252016 @default.
• W1994967425 countsByYear W19949674252017 @default.
• W1994967425 countsByYear W19949674252018 @default.
• W1994967425 countsByYear W19949674252020 @default.
• W1994967425 countsByYear W19949674252022 @default.
• W1994967425 countsByYear W19949674252023 @default.
• W1994967425 crossrefType "journal-article" @default.
• W1994967425 hasAuthorship W1994967425A5005571140 @default.
• W1994967425 hasAuthorship W1994967425A5008220682 @default.
• W1994967425 hasAuthorship W1994967425A5014431486 @default.
• W1994967425 hasAuthorship W1994967425A5026955178 @default.
• W1994967425 hasAuthorship W1994967425A5033979189 @default.
• W1994967425 hasConcept C104317684 @default.
• W1994967425 hasConcept C126322002 @default.
• W1994967425 hasConcept C131872663 @default.
• W1994967425 hasConcept C1491633281 @default.
• W1994967425 hasConcept C168007829 @default.
• W1994967425 hasConcept C172680121 @default.
• W1994967425 hasConcept C180754005 @default.
• W1994967425 hasConcept C189036908 @default.
• W1994967425 hasConcept C2776555163 @default.
• W1994967425 hasConcept C2778248108 @default.
• W1994967425 hasConcept C2778258057 @default.
• W1994967425 hasConcept C2778620579 @default.
• W1994967425 hasConcept C2779234561 @default.
• W1994967425 hasConcept C49105822 @default.
• W1994967425 hasConcept C54355233 @default.
• W1994967425 hasConcept C71924100 @default.
• W1994967425 hasConcept C86803240 @default.
• W1994967425 hasConceptScore W1994967425C104317684 @default.
• W1994967425 hasConceptScore W1994967425C126322002 @default.
• W1994967425 hasConceptScore W1994967425C131872663 @default.
• W1994967425 hasConceptScore W1994967425C1491633281 @default.
• W1994967425 hasConceptScore W1994967425C168007829 @default.
• W1994967425 hasConceptScore W1994967425C172680121 @default.
• W1994967425 hasConceptScore W1994967425C180754005 @default.
• W1994967425 hasConceptScore W1994967425C189036908 @default.
• W1994967425 hasConceptScore W1994967425C2776555163 @default.
• W1994967425 hasConceptScore W1994967425C2778248108 @default.
• W1994967425 hasConceptScore W1994967425C2778258057 @default.
• W1994967425 hasConceptScore W1994967425C2778620579 @default.
• W1994967425 hasConceptScore W1994967425C2779234561 @default.
• W1994967425 hasConceptScore W1994967425C49105822 @default.
• W1994967425 hasConceptScore W1994967425C54355233 @default.
• W1994967425 hasConceptScore W1994967425C71924100 @default.
• W1994967425 hasConceptScore W1994967425C86803240 @default.
• W1994967425 hasIssue "1-2" @default.
• W1994967425 hasLocation W19949674251 @default.
• W1994967425 hasLocation W19949674252 @default.
• W1994967425 hasOpenAccess W1994967425 @default.
• W1994967425 hasPrimaryLocation W19949674251 @default.
• W1994967425 hasRelatedWork W2000804909 @default.
• W1994967425 hasRelatedWork W2004082093 @default.
• W1994967425 hasRelatedWork W2039407466 @default.
• W1994967425 hasRelatedWork W2056752164 @default.
• W1994967425 hasRelatedWork W2070436641 @default.
• W1994967425 hasRelatedWork W2078626177 @default.

• next