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- W1994975150 abstract "These findings demonstrate that calcium antagonists reverse renal vasoconstriction in a variety of settings. The ability of calcium antagonists to augment GFR of the vasoconstricted kidney is striking and has also been demonstrated in a number of in vivo settings. These observations and others raise the possibility that calcium antagonists have potential utility in the treatment of a number of disorders characterized by renal ischemia and consequent renal insufficiency. Further studies to evaluate this possibility are required. The unique effects of calcium antagonists on GFR reflect a regional heterogeneity within the renal microcirculation and a preferential action of calcium antagonists on the afferent arteriole. Final resolution of the pharmacological basis for the renal hemodynamic actions of calcium antagonists will require a more complete understanding of the divergent activating mechanisms within the renal microcirculation." @default.
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- W1994975150 date "1988-03-01" @default.
- W1994975150 modified "2023-09-23" @default.
- W1994975150 title "Calcium Antagonists and the Renal Hemodynamic Response to Vasoconstrictors" @default.
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- W1994975150 doi "https://doi.org/10.1111/j.1749-6632.1988.tb33428.x" @default.
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