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- W1994976894 abstract "To the Editor.— Dr. Edwards in her reply to a question (212:1219, 1970) has stated that isoniazid chemoprophylaxis is recommended for anyone of any age whose tuberculin reaction from negative to positive and that appearance of a positive reaction signals the occurrence of tuberculous infection. Thus a 62-year-old physician whose reaction converted seven months after a negative tuberculin test was advised chemoprophylaxis for one year. We have shown1,2that a tuberculin test itself converts a negative tuberculin reaction to a positive one in a substantial number of persons in the absence of tuberculous infection. Such conversions as a result of the previous tuberculin test increased in frequency with age and could be more frequent in areas with high prevalence of nonspecific sensitivity. The physician given the advice came from New York, an area from which 15% to 19% of the life-time Navy recruits gave 4-mm or larger reactions" @default.
- W1994976894 created "2016-06-24" @default.
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- W1994976894 date "1970-10-19" @default.
- W1994976894 modified "2023-09-25" @default.
- W1994976894 title "Tuberculin Skin Test Conversion" @default.
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- W1994976894 doi "https://doi.org/10.1001/jama.1970.03180030113033" @default.
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