Matches in SemOpenAlex for { <https://semopenalex.org/work/W1994984192> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W1994984192 abstract "Effect of topical treatments with BV-araU was tested in cutaneous infections of shaved Balb/c mice with herpes simplex virus type 1. Evolution of zosteriform skin lesions associated with infection with a low virulent KOS(S) strain was almost completely suppressed by treatments with 5% BV-araU cream given 4 times daily for 5 days starting 1 day after inoculation. This effect was equivalent to that of Zovirax Cream including 5% acyclovir. One percent BV-araU cream was also effective in inhibiting progression of symptoms, while 0.2% cream was not effective. Five percent BV-araU cream significantly suppressed progression of skin lesion even if initiation of treatment was delayed to 2 days after infection. However, the efficacy was diminished by further delay in starting treatment. The effect of BV-araU cream was also evident during infection of immunosuppressed mice. Virus titers in the skin tissue encompassing the inoculation site of mice decreased the day after the first treatment. In the lower flank site, virus replication was almost completely suppressed by the treatment beginning 1 day postinfection. Topical application of BV-araU may be useful therapy for HSV-1 infections in humans, including immunocompromised patients." @default.
- W1994984192 created "2016-06-24" @default.
- W1994984192 creator A5030921201 @default.
- W1994984192 creator A5038089178 @default.
- W1994984192 creator A5076083486 @default.
- W1994984192 creator A5088752894 @default.
- W1994984192 date "1993-05-01" @default.
- W1994984192 modified "2023-09-27" @default.
- W1994984192 title "Topical treatment with BV-araU of immunosuppressed and immunocompetent shaved mice cutaneously infected with herpes simplex virus type 1" @default.
- W1994984192 cites W1851936098 @default.
- W1994984192 cites W1966024990 @default.
- W1994984192 cites W1978713135 @default.
- W1994984192 cites W1988867083 @default.
- W1994984192 cites W1990938465 @default.
- W1994984192 cites W2037682264 @default.
- W1994984192 cites W2049816820 @default.
- W1994984192 cites W2058685119 @default.
- W1994984192 cites W2081581581 @default.
- W1994984192 cites W2092186003 @default.
- W1994984192 cites W2133081554 @default.
- W1994984192 cites W2137562741 @default.
- W1994984192 cites W2145090218 @default.
- W1994984192 cites W2148919763 @default.
- W1994984192 cites W2282905018 @default.
- W1994984192 cites W1980969352 @default.
- W1994984192 doi "https://doi.org/10.1016/0166-3542(93)90066-r" @default.
- W1994984192 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8391248" @default.
- W1994984192 hasPublicationYear "1993" @default.
- W1994984192 type Work @default.
- W1994984192 sameAs 1994984192 @default.
- W1994984192 citedByCount "6" @default.
- W1994984192 crossrefType "journal-article" @default.
- W1994984192 hasAuthorship W1994984192A5030921201 @default.
- W1994984192 hasAuthorship W1994984192A5038089178 @default.
- W1994984192 hasAuthorship W1994984192A5076083486 @default.
- W1994984192 hasAuthorship W1994984192A5088752894 @default.
- W1994984192 hasConcept C142724271 @default.
- W1994984192 hasConcept C159047783 @default.
- W1994984192 hasConcept C180032290 @default.
- W1994984192 hasConcept C203014093 @default.
- W1994984192 hasConcept C2522874641 @default.
- W1994984192 hasConcept C2781156865 @default.
- W1994984192 hasConcept C2781196997 @default.
- W1994984192 hasConcept C32611913 @default.
- W1994984192 hasConcept C71924100 @default.
- W1994984192 hasConceptScore W1994984192C142724271 @default.
- W1994984192 hasConceptScore W1994984192C159047783 @default.
- W1994984192 hasConceptScore W1994984192C180032290 @default.
- W1994984192 hasConceptScore W1994984192C203014093 @default.
- W1994984192 hasConceptScore W1994984192C2522874641 @default.
- W1994984192 hasConceptScore W1994984192C2781156865 @default.
- W1994984192 hasConceptScore W1994984192C2781196997 @default.
- W1994984192 hasConceptScore W1994984192C32611913 @default.
- W1994984192 hasConceptScore W1994984192C71924100 @default.
- W1994984192 hasLocation W19949841921 @default.
- W1994984192 hasLocation W19949841922 @default.
- W1994984192 hasOpenAccess W1994984192 @default.
- W1994984192 hasPrimaryLocation W19949841921 @default.
- W1994984192 hasRelatedWork W1577363748 @default.
- W1994984192 hasRelatedWork W1968853355 @default.
- W1994984192 hasRelatedWork W1970382704 @default.
- W1994984192 hasRelatedWork W2018339810 @default.
- W1994984192 hasRelatedWork W2022308173 @default.
- W1994984192 hasRelatedWork W2028284080 @default.
- W1994984192 hasRelatedWork W2070480238 @default.
- W1994984192 hasRelatedWork W2093298400 @default.
- W1994984192 hasRelatedWork W2132880522 @default.
- W1994984192 hasRelatedWork W2169397754 @default.
- W1994984192 isParatext "false" @default.
- W1994984192 isRetracted "false" @default.
- W1994984192 magId "1994984192" @default.
- W1994984192 workType "article" @default.