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• W1994986522 abstract "To facilitate the delivery of genetic material, the use of appropriate carriers such as polymers is necessary. Nanoparticles comprising of chitosan-alginate polymers were formed through pregel preparation method. Chi/Alg nanoparticles had a mean Z-Average diameter of 161.8 nm and mean zeta 29.3 mV, respectively. The ability of plasmid-complex in preventing DNA migration showed Chi/Alg nanoparticles have great capacity to maintain plasmid. The efficiency of nanoparticles for transfection of pEGFP-N1 plasmid in the cultured HEK 293 cells was measured by flow cytometry. Cell viability assays indicated that nanoparticles had no toxic effect on HEK 293 cells after 4 or 24 h. Our suitable candidate for gene delivery would be alg/chi nanoparticles." @default.
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• W1994986522 date "2015-03-01" @default.
• W1994986522 modified "2023-10-14" @default.
• W1994986522 title "Hydrogel nanoparticle encapsulated plasmid as a suitable gene delivery system" @default.
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• W1994986522 doi "https://doi.org/10.3103/s0095452715020097" @default.
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