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- W1995014239 abstract "The influence of high dietary fat on the toxicity of diacetoxyscirpenol (DAS) was investigated in a 2 x 5 factorial arrangement of treatments (6 and 12% fat, and 0, 1, 2, 4, and 8 micrograms DAS/g diet). The 3-wk body weight was decreased (P less than .0001) by DAS, but fat had no significant (P less than .05) effect. There was a highly significant (P less than .0059) interaction manifested at the higher levels of DAS by a greater decrease in body weight in the high-fat diet than in the low-fat diet. Neither feed conversion nor percentage of fat in fecal material were affected significantly (P less than .05) by DAS. These data were consistent with the high-fat diet promoting lipid micellar absorption of DAS and with DAS, once absorbed, inhibiting protein synthesis at the ribosomal level, a well established mechanism of action for trichothecene toxins such as DAS." @default.
- W1995014239 created "2016-06-24" @default.
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- W1995014239 date "1991-11-01" @default.
- W1995014239 modified "2023-10-16" @default.
- W1995014239 title "High Dietary Fat Increases Toxicity of Diacetoxyscirpenol in Chickens" @default.
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- W1995014239 doi "https://doi.org/10.3382/ps.0702271" @default.
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