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• W1995015912 abstract "ObjectiveTo compare endometrial dating and ultrasound texture in a natural cycle before IVF and relate these to outcome and to fertile references.DesignProspective study with a fertile reference group.SettingFour university IVF clinics.Patient(s)Seventy-five IVF patients and 21 fertile women.Intervention(s)Ultrasound, biopsy, blood sampling. In vitro fertilization–ET in the following cycle.Main Outcome Measure(s)Endometrial evaluation, P, IVF outcome.Result(s)At day LH+7, 42% infertile vs. 67% fertile women demonstrated endometria that were in phase (statistically nonsignificant difference). Nine percent had an accelerated endometrium, and 47% (infertile) vs. 24% (fertile) had a delayed endometrium (statistically nonsignificant difference). Statistically significantly fewer women with tubal factor and no hydrosalpinges had an endometrium in phase (20%) than was the case in fertile women (67%). Dating could not predict outcome. Statistically significantly more women in the hydrosalpinx group had a visible midline at day LH+7 compared with the case in other infertile groups. Forty-three percent conceived after IVF-ET. Plasma P was statistically significantly lower in nonpregnant women compared with in women with ongoing pregnancies and with fertile controls. A periovulatory hyperechogenic endometrium resulted in no ongoing pregnancies.Conclusion(s)In a natural cycle preceding IVF, a low midluteal P level predicts a low implantation rate. A periovulatory hyperechogenic endometrium or hydrosalpinges visible at ultrasound may have some predictive value. Endometrial dating was of no help. To compare endometrial dating and ultrasound texture in a natural cycle before IVF and relate these to outcome and to fertile references. Prospective study with a fertile reference group. Four university IVF clinics. Seventy-five IVF patients and 21 fertile women. Ultrasound, biopsy, blood sampling. In vitro fertilization–ET in the following cycle. Endometrial evaluation, P, IVF outcome. At day LH+7, 42% infertile vs. 67% fertile women demonstrated endometria that were in phase (statistically nonsignificant difference). Nine percent had an accelerated endometrium, and 47% (infertile) vs. 24% (fertile) had a delayed endometrium (statistically nonsignificant difference). Statistically significantly fewer women with tubal factor and no hydrosalpinges had an endometrium in phase (20%) than was the case in fertile women (67%). Dating could not predict outcome. Statistically significantly more women in the hydrosalpinx group had a visible midline at day LH+7 compared with the case in other infertile groups. Forty-three percent conceived after IVF-ET. Plasma P was statistically significantly lower in nonpregnant women compared with in women with ongoing pregnancies and with fertile controls. A periovulatory hyperechogenic endometrium resulted in no ongoing pregnancies. In a natural cycle preceding IVF, a low midluteal P level predicts a low implantation rate. A periovulatory hyperechogenic endometrium or hydrosalpinges visible at ultrasound may have some predictive value. Endometrial dating was of no help." @default.
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• W1995015912 date "2006-11-01" @default.
• W1995015912 modified "2023-09-27" @default.
• W1995015912 title "Ultrasound characteristics and histological dating of the endometrium in a natural cycle in infertile women compared with fertile controls" @default.
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• W1995015912 doi "https://doi.org/10.1016/j.fertnstert.2006.03.052" @default.
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