Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995048910> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W1995048910 endingPage "94" @default.
- W1995048910 startingPage "89" @default.
- W1995048910 abstract "Membrane lipid peroxidation processes yield products that may react with DNA and proteins to cause oxidative modifications. Recently, we demonstrated that the control of cytosolic redox balance and the cellular defense against oxidative damage is one of the primary functions of cytosolic NADP+ -dependent isocitrate dehydrogenase (IDPc) through to supply NADPH for antioxidant systems. The protective role of IDPc against lipid peroxidation-mediated apoptosis in U937 cells was investigated in control and cells pre-treated with oxlalomalate, a competitive inhibitor of IDPc. Upon exposure to 2,2'-azobis (2-amidinopropane) hydrochloride (AAPH) to U937 cells, which induces lipid peroxidation in membranes, the susceptibility to apoptosis was higher in oxalomalate-treated cells as compared to control cells. The results suggest that IDPc plays an important protective role in apoptosis of U937 cells induced by lipid peroxidation-mediated oxidative stress." @default.
- W1995048910 created "2016-06-24" @default.
- W1995048910 creator A5011900177 @default.
- W1995048910 creator A5016006113 @default.
- W1995048910 creator A5037699405 @default.
- W1995048910 creator A5090237506 @default.
- W1995048910 date "2005-01-01" @default.
- W1995048910 modified "2023-10-11" @default.
- W1995048910 title "Oxalomalate, a competitive inhibitor of NADP<sup>+</sup>-dependent isocitrate dehydrogenase, regulates lipid peroxidation-mediated apoptosis in U937 cells" @default.
- W1995048910 cites W1738677317 @default.
- W1995048910 cites W1934775191 @default.
- W1995048910 cites W2025853482 @default.
- W1995048910 cites W2034377978 @default.
- W1995048910 cites W2042754566 @default.
- W1995048910 cites W2046452071 @default.
- W1995048910 cites W2052229224 @default.
- W1995048910 cites W2056593089 @default.
- W1995048910 cites W2089570422 @default.
- W1995048910 cites W2090561217 @default.
- W1995048910 cites W2108609254 @default.
- W1995048910 cites W2135749989 @default.
- W1995048910 cites W2158254997 @default.
- W1995048910 cites W4245957869 @default.
- W1995048910 cites W4254479325 @default.
- W1995048910 cites W4293103701 @default.
- W1995048910 doi "https://doi.org/10.1080/10715760400022996" @default.
- W1995048910 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15875816" @default.
- W1995048910 hasPublicationYear "2005" @default.
- W1995048910 type Work @default.
- W1995048910 sameAs 1995048910 @default.
- W1995048910 citedByCount "6" @default.
- W1995048910 countsByYear W19950489102016 @default.
- W1995048910 countsByYear W19950489102018 @default.
- W1995048910 crossrefType "journal-article" @default.
- W1995048910 hasAuthorship W1995048910A5011900177 @default.
- W1995048910 hasAuthorship W1995048910A5016006113 @default.
- W1995048910 hasAuthorship W1995048910A5037699405 @default.
- W1995048910 hasAuthorship W1995048910A5090237506 @default.
- W1995048910 hasConcept C108634530 @default.
- W1995048910 hasConcept C181199279 @default.
- W1995048910 hasConcept C185592680 @default.
- W1995048910 hasConcept C190283241 @default.
- W1995048910 hasConcept C2776151105 @default.
- W1995048910 hasConcept C2777150147 @default.
- W1995048910 hasConcept C2778004101 @default.
- W1995048910 hasConcept C2780829032 @default.
- W1995048910 hasConcept C55493867 @default.
- W1995048910 hasConcept C86803240 @default.
- W1995048910 hasConcept C95444343 @default.
- W1995048910 hasConceptScore W1995048910C108634530 @default.
- W1995048910 hasConceptScore W1995048910C181199279 @default.
- W1995048910 hasConceptScore W1995048910C185592680 @default.
- W1995048910 hasConceptScore W1995048910C190283241 @default.
- W1995048910 hasConceptScore W1995048910C2776151105 @default.
- W1995048910 hasConceptScore W1995048910C2777150147 @default.
- W1995048910 hasConceptScore W1995048910C2778004101 @default.
- W1995048910 hasConceptScore W1995048910C2780829032 @default.
- W1995048910 hasConceptScore W1995048910C55493867 @default.
- W1995048910 hasConceptScore W1995048910C86803240 @default.
- W1995048910 hasConceptScore W1995048910C95444343 @default.
- W1995048910 hasIssue "1" @default.
- W1995048910 hasLocation W19950489101 @default.
- W1995048910 hasLocation W19950489102 @default.
- W1995048910 hasOpenAccess W1995048910 @default.
- W1995048910 hasPrimaryLocation W19950489101 @default.
- W1995048910 hasRelatedWork W1520041382 @default.
- W1995048910 hasRelatedWork W1557898514 @default.
- W1995048910 hasRelatedWork W2058770031 @default.
- W1995048910 hasRelatedWork W2266544059 @default.
- W1995048910 hasRelatedWork W2791181644 @default.
- W1995048910 hasRelatedWork W2972415784 @default.
- W1995048910 hasRelatedWork W2978950873 @default.
- W1995048910 hasRelatedWork W3029726485 @default.
- W1995048910 hasRelatedWork W3185195364 @default.
- W1995048910 hasRelatedWork W346701668 @default.
- W1995048910 hasVolume "39" @default.
- W1995048910 isParatext "false" @default.
- W1995048910 isRetracted "false" @default.
- W1995048910 magId "1995048910" @default.
- W1995048910 workType "article" @default.