FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995072017> ?p ?o ?g. }

• W1995072017 endingPage "e83805" @default.
• W1995072017 startingPage "e83805" @default.
• W1995072017 abstract "Inflammation-induced activation of endothelium constitutes one of the earliest changes during atherogenesis. New imaging techniques that allow detecting activated endothelial cells can improve the identification of persons at high cardiovascular risk in early stages. Quantum dots (QDs) have attractive optical properties such as bright fluorescence and high photostability, and have been increasingly studied and developed for bio-imaging and bio-targeting applications. We report here the development of vascular cell adhesion molecule-1 binding peptide (VCAM-1 binding peptide) functionalized QDs (VQDs) from amino QDs. It was found that the QD fluorescence signal in tumor necrosis factor [Formula: see text] (TNF-[Formula: see text]) treated endothelial cells in vitro was significantly higher when these cells were labeled with VQDs than amino QDs. The VQD labeling of TNF-[Formula: see text]-treated endothelial cells was VCAM-1 specific since pre-incubation with recombinant VCAM-1 blocked cells' uptake of VQDs. Our ex vivo and in vivo experiments showed that in the inflamed endothelium, QD fluorescence signal from VQDs was also much stronger than that of amino QDs. Moreover, we observed that the QD fluorescence peak was significantly blue-shifted after VQDs interacted with aortic endothelial cells in vivo and in vitro. A similar blue-shift was observed after VQDs were incubated with recombinant VCAM-1 in tube. We anticipate that the specific interaction between VQDs and VCAM-1 and the blue-shift of the QD fluorescence peak can be very useful for VCAM-1 detection in vivo." @default.
• W1995072017 created "2016-06-24" @default.
• W1995072017 creator A5002409069 @default.
• W1995072017 creator A5011594220 @default.
• W1995072017 creator A5027475930 @default.
• W1995072017 creator A5039027696 @default.
• W1995072017 creator A5059443988 @default.
• W1995072017 creator A5061402622 @default.
• W1995072017 creator A5089632319 @default.
• W1995072017 date "2013-12-31" @default.
• W1995072017 modified "2023-10-11" @default.
• W1995072017 title "Characterization of VCAM-1-Binding Peptide-Functionalized Quantum Dots for Molecular Imaging of Inflamed Endothelium" @default.
• W1995072017 cites W1964203864 @default.
• W1995072017 cites W1968101875 @default.
• W1995072017 cites W1969043210 @default.
• W1995072017 cites W1977744096 @default.
• W1995072017 cites W1977793874 @default.
• W1995072017 cites W1979125328 @default.
• W1995072017 cites W1987838171 @default.
• W1995072017 cites W1994719445 @default.
• W1995072017 cites W1997434152 @default.
• W1995072017 cites W2008921799 @default.
• W1995072017 cites W2014700803 @default.
• W1995072017 cites W2015230474 @default.
• W1995072017 cites W2018588810 @default.
• W1995072017 cites W2019026961 @default.
• W1995072017 cites W2029439561 @default.
• W1995072017 cites W2035994173 @default.
• W1995072017 cites W2040585929 @default.
• W1995072017 cites W2045204954 @default.
• W1995072017 cites W2046781132 @default.
• W1995072017 cites W2057616332 @default.
• W1995072017 cites W2058525339 @default.
• W1995072017 cites W2064548903 @default.
• W1995072017 cites W2064863505 @default.
• W1995072017 cites W2071502809 @default.
• W1995072017 cites W2078964476 @default.
• W1995072017 cites W2081040081 @default.
• W1995072017 cites W2091397405 @default.
• W1995072017 cites W2091611656 @default.
• W1995072017 cites W2095490474 @default.
• W1995072017 cites W2095555713 @default.
• W1995072017 cites W2101037111 @default.
• W1995072017 cites W2112101570 @default.
• W1995072017 cites W2148924929 @default.
• W1995072017 cites W2154321074 @default.
• W1995072017 cites W2159087408 @default.
• W1995072017 cites W2168136625 @default.
• W1995072017 doi "https://doi.org/10.1371/journal.pone.0083805" @default.
• W1995072017 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3877406" @default.
• W1995072017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24391829" @default.
• W1995072017 hasPublicationYear "2013" @default.
• W1995072017 type Work @default.
• W1995072017 sameAs 1995072017 @default.
• W1995072017 citedByCount "23" @default.
• W1995072017 countsByYear W19950720172014 @default.
• W1995072017 countsByYear W19950720172015 @default.
• W1995072017 countsByYear W19950720172016 @default.
• W1995072017 countsByYear W19950720172017 @default.
• W1995072017 countsByYear W19950720172018 @default.
• W1995072017 countsByYear W19950720172019 @default.
• W1995072017 countsByYear W19950720172020 @default.
• W1995072017 countsByYear W19950720172021 @default.
• W1995072017 countsByYear W19950720172022 @default.
• W1995072017 countsByYear W19950720172023 @default.
• W1995072017 crossrefType "journal-article" @default.
• W1995072017 hasAuthorship W1995072017A5002409069 @default.
• W1995072017 hasAuthorship W1995072017A5011594220 @default.
• W1995072017 hasAuthorship W1995072017A5027475930 @default.
• W1995072017 hasAuthorship W1995072017A5039027696 @default.
• W1995072017 hasAuthorship W1995072017A5059443988 @default.
• W1995072017 hasAuthorship W1995072017A5061402622 @default.
• W1995072017 hasAuthorship W1995072017A5089632319 @default.
• W1995072017 hasBestOaLocation W19950720171 @default.
• W1995072017 hasConcept C104317684 @default.
• W1995072017 hasConcept C121332964 @default.
• W1995072017 hasConcept C123012128 @default.
• W1995072017 hasConcept C12554922 @default.
• W1995072017 hasConcept C134018914 @default.
• W1995072017 hasConcept C1491633281 @default.
• W1995072017 hasConcept C150903083 @default.
• W1995072017 hasConcept C153911025 @default.
• W1995072017 hasConcept C17991360 @default.
• W1995072017 hasConcept C185592680 @default.
• W1995072017 hasConcept C202751555 @default.
• W1995072017 hasConcept C203014093 @default.
• W1995072017 hasConcept C207001950 @default.
• W1995072017 hasConcept C26291073 @default.
• W1995072017 hasConcept C2776985958 @default.
• W1995072017 hasConcept C2776992346 @default.
• W1995072017 hasConcept C2779281246 @default.
• W1995072017 hasConcept C40767141 @default.
• W1995072017 hasConcept C55493867 @default.
• W1995072017 hasConcept C57477423 @default.
• W1995072017 hasConcept C62520636 @default.
• W1995072017 hasConcept C85789140 @default.
• W1995072017 hasConcept C86803240 @default.
• W1995072017 hasConcept C91881484 @default.

• next