Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995087603> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W1995087603 endingPage "777" @default.
- W1995087603 startingPage "771" @default.
- W1995087603 abstract "Previously we reported that heat-treatment of lysozyme at 80°C for 20 min in pH 6.0 (HL80/6) greatly promoted its antimicrobial action to Gram-negative bacteria without detrimental effects on its inherent action to Gram-positive ones. In this study the effects of sucrose and NaCl on the promoted antimicrobial activity of HL80/6 and synergy with glycine were investigated. This potent antimicrobial lysozyme (HL80/6) retained 54% of the native enzymatic activity. The enhanced bactericidal action of HL80/6 against Escherichia coli K12 was gradually decreased with increasing sucrose and NaCl concentration in the medium, where complete suppression was observed at 2% sucrose and 0.1% NaCl. On the other hand, 1% NaCl concentration was required to suppress the antimicrobial activity against Staphylococcus aureus of either native lysozyme (NLz) or HL80/6, while sucrose up to 8% had no detectable inhibitory effect on this strain. However, similar doses of sucrose or NaCl had no effect on the enzymatic activity of both NLz and HL80/6, indicating that the antimicrobial action of HL80/6 is independent of its muramidase activity. HL80/6 lysozyme, but not NLz, exhibited good synergy with glycine against Gram-negative bacteria even in the presence of the inhibitory doses of sucrose or NaCl, suggesting a possible application in food industry as a food preservative. Thus, the results introduce an interesting finding that partial denaturation of lysozyme can induce its antimicrobial specificity to include the food-borne Gram-negative pathogens and heralded fascinating opportunities for application of HL80/6 with glycine in formulated food systems." @default.
- W1995087603 created "2016-06-24" @default.
- W1995087603 creator A5004210412 @default.
- W1995087603 creator A5041944503 @default.
- W1995087603 creator A5058845000 @default.
- W1995087603 creator A5070014527 @default.
- W1995087603 date "1996-12-01" @default.
- W1995087603 modified "2023-09-23" @default.
- W1995087603 title "Antimicrobial synergism of partially-denatured lysozyme with glycine: effect of sucrose and sodium chloride" @default.
- W1995087603 cites W1567413266 @default.
- W1995087603 cites W1919739622 @default.
- W1995087603 cites W1986438373 @default.
- W1995087603 cites W2006370393 @default.
- W1995087603 cites W2028184134 @default.
- W1995087603 cites W2043934321 @default.
- W1995087603 cites W2055598466 @default.
- W1995087603 cites W2075251218 @default.
- W1995087603 cites W2113209854 @default.
- W1995087603 cites W2126739759 @default.
- W1995087603 cites W2316317136 @default.
- W1995087603 doi "https://doi.org/10.1016/s0963-9969(97)00006-9" @default.
- W1995087603 hasPublicationYear "1996" @default.
- W1995087603 type Work @default.
- W1995087603 sameAs 1995087603 @default.
- W1995087603 citedByCount "12" @default.
- W1995087603 countsByYear W19950876032016 @default.
- W1995087603 countsByYear W19950876032017 @default.
- W1995087603 countsByYear W19950876032018 @default.
- W1995087603 countsByYear W19950876032020 @default.
- W1995087603 countsByYear W19950876032021 @default.
- W1995087603 crossrefType "journal-article" @default.
- W1995087603 hasAuthorship W1995087603A5004210412 @default.
- W1995087603 hasAuthorship W1995087603A5041944503 @default.
- W1995087603 hasAuthorship W1995087603A5058845000 @default.
- W1995087603 hasAuthorship W1995087603A5070014527 @default.
- W1995087603 hasConcept C178790620 @default.
- W1995087603 hasConcept C181199279 @default.
- W1995087603 hasConcept C185592680 @default.
- W1995087603 hasConcept C2776966407 @default.
- W1995087603 hasConcept C2777756961 @default.
- W1995087603 hasConcept C2778597767 @default.
- W1995087603 hasConcept C2909531343 @default.
- W1995087603 hasConcept C31903555 @default.
- W1995087603 hasConcept C4937899 @default.
- W1995087603 hasConcept C515207424 @default.
- W1995087603 hasConcept C523546767 @default.
- W1995087603 hasConcept C537181965 @default.
- W1995087603 hasConcept C54355233 @default.
- W1995087603 hasConcept C55493867 @default.
- W1995087603 hasConcept C67031304 @default.
- W1995087603 hasConcept C86803240 @default.
- W1995087603 hasConceptScore W1995087603C178790620 @default.
- W1995087603 hasConceptScore W1995087603C181199279 @default.
- W1995087603 hasConceptScore W1995087603C185592680 @default.
- W1995087603 hasConceptScore W1995087603C2776966407 @default.
- W1995087603 hasConceptScore W1995087603C2777756961 @default.
- W1995087603 hasConceptScore W1995087603C2778597767 @default.
- W1995087603 hasConceptScore W1995087603C2909531343 @default.
- W1995087603 hasConceptScore W1995087603C31903555 @default.
- W1995087603 hasConceptScore W1995087603C4937899 @default.
- W1995087603 hasConceptScore W1995087603C515207424 @default.
- W1995087603 hasConceptScore W1995087603C523546767 @default.
- W1995087603 hasConceptScore W1995087603C537181965 @default.
- W1995087603 hasConceptScore W1995087603C54355233 @default.
- W1995087603 hasConceptScore W1995087603C55493867 @default.
- W1995087603 hasConceptScore W1995087603C67031304 @default.
- W1995087603 hasConceptScore W1995087603C86803240 @default.
- W1995087603 hasIssue "8" @default.
- W1995087603 hasLocation W19950876031 @default.
- W1995087603 hasOpenAccess W1995087603 @default.
- W1995087603 hasPrimaryLocation W19950876031 @default.
- W1995087603 hasRelatedWork W1995087603 @default.
- W1995087603 hasRelatedWork W2169210006 @default.
- W1995087603 hasRelatedWork W2361187707 @default.
- W1995087603 hasRelatedWork W2601613475 @default.
- W1995087603 hasRelatedWork W2622523440 @default.
- W1995087603 hasRelatedWork W2892638632 @default.
- W1995087603 hasRelatedWork W4211138028 @default.
- W1995087603 hasRelatedWork W4220671233 @default.
- W1995087603 hasRelatedWork W4221057800 @default.
- W1995087603 hasRelatedWork W4296329299 @default.
- W1995087603 hasVolume "29" @default.
- W1995087603 isParatext "false" @default.
- W1995087603 isRetracted "false" @default.
- W1995087603 magId "1995087603" @default.
- W1995087603 workType "article" @default.