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- W1995096593 abstract "(Z)-8-Aryl-5-tosyl-5-azaoct-2-en-7-yn-1-ols were cycloisomerized to the corresponding cis-3-acyl-4-alkenylpyrrolidines when treated with a catalytic amount of Ph3PAuCl/AgOTf in CH2Cl2. The reaction proceeded via attack of the hydroxyl group onto the gold-activated alkynes followed by [3,3]-sigmatropic rearrangement to generate cis-3-acyl-4-alkenylpyrrolidines in good yields. This transformation can be applied to the synthesis of cis- and trans-3-acyl-4-alkenylcyclopentanes from (Z)- and (E)-8-aryloct-2-en-7-yn-1-ols, respectively." @default.
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- W1995096593 date "2010-08-10" @default.
- W1995096593 modified "2023-09-26" @default.
- W1995096593 title "Synthesis of <i>cis</i>-3-Acyl-4-alkenylpyrrolidines via Gold(I)-Catalyzed Cycloisomerization Reaction of (<i>Z</i>)-8-Aryl-5-tosyl-5-azaoct-2-en-7-yn-1-ols" @default.
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- W1995096593 doi "https://doi.org/10.1021/jo101148e" @default.
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