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• W199510174 abstract "Neuroblastoma (NB) is a neoplasm arising from embryonic neural crest cells. Primary and metastatic central nervous system (CNS) neuroblastomas are extremely rare and may involve the cerebral parenchyma, leptomeninges, or dura. Magnetic resonance imaging (MRI) plays an important role in the initial diagnosis and staging of neuroblastoma as it provides for accurate tumor localization, size, extent and metastases. The technique aids image-guided surgery, follow-up assessment of residual tumor, response to chemo-radiotherapy, diagnosing recurrence and metastases. This chapter describes routine and advanced MR imaging techniques for diagnosis of both primary and secondary CNS neuroblastoma. In addition MR appearances have been correlated with histologically observable cellular transformations. Advanced MR techniques like diffusion-weighted imaging, gradient and susceptibility weighted imaging, serve to assess cellularity, haemorrhage and necrosis, features which predict tumor behaviour. 1H and 31P MR spectroscopy can identify tissue biochemical changes within the tumor. These methods are helpful in predicting heterogeneity, aggressiveness and metastatic pattern of neuroblastoma and thus prognosis." @default.
• W199510174 created "2016-06-24" @default.
• W199510174 creator A5069116264 @default.
• W199510174 date "2011-10-03" @default.
• W199510174 modified "2023-10-03" @default.
• W199510174 title "Pediatric CNS Neuroblastoma: Magnetic Resonance Imaging and Spectroscopy" @default.
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• W199510174 doi "https://doi.org/10.1007/978-94-007-2418-1_2" @default.
• W199510174 hasPublicationYear "2011" @default.
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