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• W1995106711 abstract "The conformational changes of a 22 base-pair double-stranded DNA, anchored via one end to a quartz substrate, have been characterized using a single-pair fluorescence resonance energy transfer technique. Base-pair mismatch, a major form of DNA damage, has been found to decrease the energy transfer between a fluorescence donor and an acceptor attached to the two ends of DNA molecules with 3 and 7 mismatches, by 4.4% and 10.4%, respectively, as compared to that for perfectly matched DNA. This result suggests that the disruption of the hydrogen bonds in damaged DNA leads to increased contour length and improved flexibility." @default.
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• W1995106711 date "2005-07-14" @default.
• W1995106711 modified "2023-09-23" @default.
• W1995106711 title "Single-molecule DNA flexibility in the presence of base-pair mismatch" @default.
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• W1995106711 doi "https://doi.org/10.1063/1.1997279" @default.
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