Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995109436> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W1995109436 endingPage "798" @default.
- W1995109436 startingPage "793" @default.
- W1995109436 abstract "We sought to investigate the benefit, predictors of procedural success, and safety of pre-procedural intra-coronary fibrin-specific lytic infusion (ICL) in patients with failed prior percutaneous coronary intervention (PCI) for chronic total occlusions (CTO).Percutaneous coronary intervention for CTO remains a challenge with a high incidence of procedural failure secondary to inability to cross the occlusion with the guidewire.Eighty-five patients who underwent unsuccessful PCI procedures of CTO (more than three months' duration) had a repeat attempt of recanalization with the use of pre-procedural ICL. Patients received a weight-adjusted dose of either alteplase (tPA) (2 to 5 mg/h) or tenecteplase (TNK) (0.5 mg/h) for a total of 8 h. The total dose of ICL therapy was infused split between the guiding catheter and an intracoronary infusion catheter. A step-down multivariate logistic regression analysis was completed to determine the best predictors of procedural success. In-hospital major adverse cardiac events (MACE) including myocardial infarction, acute reocclusion, stroke, and death, as well as bleeding complications, were also examined.The procedure was successful in 46 of 85 cases (54%). Four of 85 (5%) contained dissections that did not result in perforations, tamponade, or MACE. The incidence of groin complications was 7 of 85 (8%) and of bleeding complications requiring transfusions was 3 of 85 (3.5%). On multivariate analysis, predictors of success were tapering morphology (odds ratio, 15.5; 95% confidence interval, 3.73 to 63; p = 0.0002) and lack of bridging collaterals (odds ratio, 5.08; 95% confidence interval, 1.53 to 17; p = 0.008).Intracoronary infusion of fibrin-specific thrombolytic therapy may provide a valuable and safe option for facilitating percutaneous revascularization of CTO." @default.
- W1995109436 created "2016-06-24" @default.
- W1995109436 creator A5000112460 @default.
- W1995109436 creator A5015393697 @default.
- W1995109436 creator A5024332733 @default.
- W1995109436 creator A5039649958 @default.
- W1995109436 creator A5044728702 @default.
- W1995109436 creator A5064866815 @default.
- W1995109436 date "2005-09-01" @default.
- W1995109436 modified "2023-09-27" @default.
- W1995109436 title "Intracoronary Fibrin-Specific Thrombolytic Infusion Facilitates Percutaneous Recanalization of Chronic Total Occlusion" @default.
- W1995109436 cites W1983850528 @default.
- W1995109436 cites W2010251604 @default.
- W1995109436 cites W2025372105 @default.
- W1995109436 cites W2028232205 @default.
- W1995109436 cites W2042690863 @default.
- W1995109436 cites W204631244 @default.
- W1995109436 cites W2055060088 @default.
- W1995109436 cites W2055480459 @default.
- W1995109436 cites W2063793694 @default.
- W1995109436 cites W2068400342 @default.
- W1995109436 cites W2080761758 @default.
- W1995109436 cites W2083706987 @default.
- W1995109436 cites W2091903997 @default.
- W1995109436 cites W2094666760 @default.
- W1995109436 cites W2112923132 @default.
- W1995109436 cites W2129055874 @default.
- W1995109436 cites W2164128750 @default.
- W1995109436 cites W4238013009 @default.
- W1995109436 doi "https://doi.org/10.1016/j.jacc.2005.05.055" @default.
- W1995109436 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16139127" @default.
- W1995109436 hasPublicationYear "2005" @default.
- W1995109436 type Work @default.
- W1995109436 sameAs 1995109436 @default.
- W1995109436 citedByCount "23" @default.
- W1995109436 countsByYear W19951094362013 @default.
- W1995109436 countsByYear W19951094362018 @default.
- W1995109436 countsByYear W19951094362020 @default.
- W1995109436 crossrefType "journal-article" @default.
- W1995109436 hasAuthorship W1995109436A5000112460 @default.
- W1995109436 hasAuthorship W1995109436A5015393697 @default.
- W1995109436 hasAuthorship W1995109436A5024332733 @default.
- W1995109436 hasAuthorship W1995109436A5039649958 @default.
- W1995109436 hasAuthorship W1995109436A5044728702 @default.
- W1995109436 hasAuthorship W1995109436A5064866815 @default.
- W1995109436 hasBestOaLocation W19951094361 @default.
- W1995109436 hasConcept C126322002 @default.
- W1995109436 hasConcept C141071460 @default.
- W1995109436 hasConcept C156957248 @default.
- W1995109436 hasConcept C164705383 @default.
- W1995109436 hasConcept C2779095551 @default.
- W1995109436 hasConcept C2779581417 @default.
- W1995109436 hasConcept C2780400711 @default.
- W1995109436 hasConcept C2780739214 @default.
- W1995109436 hasConcept C42219234 @default.
- W1995109436 hasConcept C45393284 @default.
- W1995109436 hasConcept C500558357 @default.
- W1995109436 hasConcept C71924100 @default.
- W1995109436 hasConceptScore W1995109436C126322002 @default.
- W1995109436 hasConceptScore W1995109436C141071460 @default.
- W1995109436 hasConceptScore W1995109436C156957248 @default.
- W1995109436 hasConceptScore W1995109436C164705383 @default.
- W1995109436 hasConceptScore W1995109436C2779095551 @default.
- W1995109436 hasConceptScore W1995109436C2779581417 @default.
- W1995109436 hasConceptScore W1995109436C2780400711 @default.
- W1995109436 hasConceptScore W1995109436C2780739214 @default.
- W1995109436 hasConceptScore W1995109436C42219234 @default.
- W1995109436 hasConceptScore W1995109436C45393284 @default.
- W1995109436 hasConceptScore W1995109436C500558357 @default.
- W1995109436 hasConceptScore W1995109436C71924100 @default.
- W1995109436 hasIssue "5" @default.
- W1995109436 hasLocation W19951094361 @default.
- W1995109436 hasLocation W19951094362 @default.
- W1995109436 hasOpenAccess W1995109436 @default.
- W1995109436 hasPrimaryLocation W19951094361 @default.
- W1995109436 hasRelatedWork W2136815123 @default.
- W1995109436 hasRelatedWork W2360532522 @default.
- W1995109436 hasRelatedWork W2372347647 @default.
- W1995109436 hasRelatedWork W2372758922 @default.
- W1995109436 hasRelatedWork W2374929624 @default.
- W1995109436 hasRelatedWork W2375584960 @default.
- W1995109436 hasRelatedWork W2390206430 @default.
- W1995109436 hasRelatedWork W2822274293 @default.
- W1995109436 hasRelatedWork W3031125000 @default.
- W1995109436 hasRelatedWork W4220751190 @default.
- W1995109436 hasVolume "46" @default.
- W1995109436 isParatext "false" @default.
- W1995109436 isRetracted "false" @default.
- W1995109436 magId "1995109436" @default.
- W1995109436 workType "article" @default.