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- W1995133074 abstract "The synthesis and secretion of chondroitin sulphate proteoglycan (CSPG) was examined in human muscle cultures during myogenesis prior to myoblast fusion and following myotube formation. Results from this study demonstrate that the major CSPG secreted into the medium had a Kav of 0.15 on Sephacryl 500 (exclusion limit of 107 Da) and contained predominantly unsulphated residues in mononucleated cell cultures but these became increasingly sulphated in postfusion cultures. Fibroblasts synthesised small amounts of a smaller molecular weight CSPG indicating that the Kav 0.15 proteoglycan is solely synthesised by cells of the myogenic lineage. These findings illustrate that sulphation of CSPG is develomentally regulated during myogenesis of human muscle cells grown under differentiating conditions." @default.
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- W1995133074 date "1986-05-01" @default.
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- W1995133074 title "Developmental changes in sulphation of chondroitin sulphate proteoglycan during myogenesis of human muscle cultures" @default.
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- W1995133074 doi "https://doi.org/10.1016/0012-1606(86)90229-0" @default.
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