Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995152152> ?p ?o ?g. }
- W1995152152 endingPage "386" @default.
- W1995152152 startingPage "371" @default.
- W1995152152 abstract "Practical circadian therapy for the cancer patient involves 3 spheres of intervention-improving lifestyle, optimizing internal biochemical milieu, and adjusting treatment times. The potential value of improving overall circadian functioning is shown in the work of Mormont et al in which pronounced rest-activity rhythms were associated with better survival in colorectal cancer patients receiving chronomodulated chemotherapy. Lifestyle interventions that may improve circadian functioning involve diet, physical activity, and mind-body therapies. A diet that is anti-inflammatory and has appropriate carbohydrate intake, as well as regular meal timing, encourages normal circadian cycles. Adequate daytime physical activity encourages restful sleep, and morning light exposure during exercise may entrain melatonin rhythms. Meditation and other mind-body therapies can reduce anxiety and depression that may disrupt sleep. Aspects of the biochemical milieu that specifically disrupt circadian functioning are inflammation and stress hormones. Inflammation and cytokine disruption can be addressed with diet, herbs, and other natural substances. Chronomodulation of chemotherapy in a US clinical setting will be discussed. A series of 12 cases will be presented of patients who experienced grade 3 to 4 toxicities with various chemotherapy regimens for colorectal cancer. When rechallenged with the same regimens administered chronotherapeutically, none of the patients experienced grade 3 to 4 toxicity. Integrating all the above treatment modalities has the potential to improve both the quality of life and disease outcomes in cancer patients." @default.
- W1995152152 created "2016-06-24" @default.
- W1995152152 creator A5000560457 @default.
- W1995152152 creator A5003611411 @default.
- W1995152152 creator A5006373654 @default.
- W1995152152 creator A5006402320 @default.
- W1995152152 creator A5011522767 @default.
- W1995152152 creator A5016513775 @default.
- W1995152152 creator A5021208641 @default.
- W1995152152 creator A5039775951 @default.
- W1995152152 creator A5048543541 @default.
- W1995152152 creator A5064336529 @default.
- W1995152152 date "2009-12-01" @default.
- W1995152152 modified "2023-09-27" @default.
- W1995152152 title "Making Circadian Cancer Therapy Practical" @default.
- W1995152152 cites W1534458874 @default.
- W1995152152 cites W1675116923 @default.
- W1995152152 cites W1836945052 @default.
- W1995152152 cites W1926677772 @default.
- W1995152152 cites W1935468480 @default.
- W1995152152 cites W1972472202 @default.
- W1995152152 cites W1973655938 @default.
- W1995152152 cites W1976785629 @default.
- W1995152152 cites W1983252826 @default.
- W1995152152 cites W1989396540 @default.
- W1995152152 cites W1997151200 @default.
- W1995152152 cites W1997157023 @default.
- W1995152152 cites W1997310607 @default.
- W1995152152 cites W2011013456 @default.
- W1995152152 cites W2011136410 @default.
- W1995152152 cites W2011460555 @default.
- W1995152152 cites W2012462539 @default.
- W1995152152 cites W2022568586 @default.
- W1995152152 cites W2023256644 @default.
- W1995152152 cites W2032900901 @default.
- W1995152152 cites W2037322134 @default.
- W1995152152 cites W2037909222 @default.
- W1995152152 cites W2047515951 @default.
- W1995152152 cites W2051047481 @default.
- W1995152152 cites W2057798107 @default.
- W1995152152 cites W2059019487 @default.
- W1995152152 cites W2059381322 @default.
- W1995152152 cites W2060819195 @default.
- W1995152152 cites W2061440677 @default.
- W1995152152 cites W2063269649 @default.
- W1995152152 cites W2074945663 @default.
- W1995152152 cites W2075441909 @default.
- W1995152152 cites W2076366897 @default.
- W1995152152 cites W2076858653 @default.
- W1995152152 cites W2078244481 @default.
- W1995152152 cites W2082374637 @default.
- W1995152152 cites W2083966369 @default.
- W1995152152 cites W2084016807 @default.
- W1995152152 cites W2088421395 @default.
- W1995152152 cites W2088452008 @default.
- W1995152152 cites W2089320769 @default.
- W1995152152 cites W2091912666 @default.
- W1995152152 cites W2097562152 @default.
- W1995152152 cites W2104183364 @default.
- W1995152152 cites W2106845199 @default.
- W1995152152 cites W2110176899 @default.
- W1995152152 cites W2111292033 @default.
- W1995152152 cites W2112727687 @default.
- W1995152152 cites W2113442652 @default.
- W1995152152 cites W2114935673 @default.
- W1995152152 cites W2120366984 @default.
- W1995152152 cites W2128451984 @default.
- W1995152152 cites W2133399075 @default.
- W1995152152 cites W2134105940 @default.
- W1995152152 cites W2138144859 @default.
- W1995152152 cites W2138849307 @default.
- W1995152152 cites W2140033791 @default.
- W1995152152 cites W2144651395 @default.
- W1995152152 cites W2146024084 @default.
- W1995152152 cites W2148537092 @default.
- W1995152152 cites W2148896884 @default.
- W1995152152 cites W2149684797 @default.
- W1995152152 cites W2149923124 @default.
- W1995152152 cites W2151776730 @default.
- W1995152152 cites W2152172206 @default.
- W1995152152 cites W2157015549 @default.
- W1995152152 cites W2163527944 @default.
- W1995152152 cites W2163693517 @default.
- W1995152152 cites W2165208289 @default.
- W1995152152 cites W2166647521 @default.
- W1995152152 cites W2167409896 @default.
- W1995152152 cites W2168679480 @default.
- W1995152152 cites W2169887727 @default.
- W1995152152 cites W2172146703 @default.
- W1995152152 cites W2197375803 @default.
- W1995152152 cites W27767286 @default.
- W1995152152 cites W4236169968 @default.
- W1995152152 cites W4291113428 @default.
- W1995152152 doi "https://doi.org/10.1177/1534735409352028" @default.
- W1995152152 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20042412" @default.
- W1995152152 hasPublicationYear "2009" @default.
- W1995152152 type Work @default.
- W1995152152 sameAs 1995152152 @default.