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- W1995167269 abstract "Abstract Derivatization, or chemical modification of analytes, is often required for species that are only weakly detectable by common spectroscopic methods. Derivatization is most commonly performed in homogeneous solution or using phase‐transfer catalyzed reactions. However, the use of solid phase supports for performing the same reactions has a number of advantages. The sample can be “cleaned up” on the same phase, eliminating interfering matrix components or excess reagent. The process naturally concentrates the analyte, providing higher sensitivity, but also, under favorable circumstances, provides for more efficient reactions relative to solutions of the same original concentration. This review explores the uses to which such supports have been put, primarily in fluorescence derivatization for chromatographic applications. Some of the considerations in applying these techniques are described, and they are shown to be an extremely useful format for derivatization." @default.
- W1995167269 created "2016-06-24" @default.
- W1995167269 creator A5022213537 @default.
- W1995167269 creator A5062318588 @default.
- W1995167269 date "2005-11-01" @default.
- W1995167269 modified "2023-09-26" @default.
- W1995167269 title "The Use of Solid‐Phase Supports for Derivatization in Chromatography and Spectroscopy" @default.
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- W1995167269 doi "https://doi.org/10.1080/05704920500250334" @default.
- W1995167269 hasPublicationYear "2005" @default.
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