FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995184116> ?p ?o ?g. }

• W1995184116 endingPage "293" @default.
• W1995184116 startingPage "287" @default.
• W1995184116 abstract "<i>Background:</i> Angiotensin-converting enzyme (ACE) inhibitors have been reported to reduce the response to erythropoietin (EPO) administration in chronic hemodialysis patients, but the mechanism for this effect has not yet been clarified. To clarify the mechanism of ACE inhibitors- and angiotensin II type 1 (AT1) receptor antagonist-induced anemia in hemodialysis patients, we examined the effect of ACE inhibitors and AT1 receptor antagonist on burst-forming units-erythroid (BFU-E) in the peripheral blood of hemodialysis patients and healthy controls in vitro. <i>Methods:</i> Peripheral blood mononuclear cells (PBMNCs) were isolated by gradient centrifugation from 10 patients on regular hemodialysis and 7 healthy control volunteers. A colony assay of hematopoietic progenitors was performed using the methylcellulose culture system. PBMNCs of 1 or 2 × 10⁵ were plated in a medium containing EPO with various concentrations of ACE inhibitors or AT1 receptor antagonist and incubated for 14 days. Colonies of BFU-E were counted under an inverted microscope. <i>Results:</i> The PBMNCs from the chronic hemodialysis patients formed fewer BFU-Es than those from healthy volunteers. AT1 receptor antagonist in both healthy volunteers and hemodialysis patients suppressed the number of BFU-Es. The ACE inhibitors produced a smaller effect than the AT1 receptor antagonist. <i>Conclusion:</i> AT1 receptor blockade can directly inhibit erythropoiesis in vitro." @default.
• W1995184116 created "2016-06-24" @default.
• W1995184116 creator A5008500153 @default.
• W1995184116 creator A5027281956 @default.
• W1995184116 creator A5034553302 @default.
• W1995184116 creator A5038452939 @default.
• W1995184116 creator A5051130816 @default.
• W1995184116 date "2003-01-01" @default.
• W1995184116 modified "2023-10-01" @default.
• W1995184116 title "Effects of an Angiotensin II Receptor Antagonist and Angiotensin-Converting Enzyme Inhibitors on Burst Forming Units-Erythroid in Chronic Hemodialysis Patients" @default.
• W1995184116 cites W1984148894 @default.
• W1995184116 cites W2002782759 @default.
• W1995184116 cites W2003488252 @default.
• W1995184116 cites W2019931350 @default.
• W1995184116 cites W2041792559 @default.
• W1995184116 cites W2060526183 @default.
• W1995184116 cites W2061776631 @default.
• W1995184116 cites W2062228467 @default.
• W1995184116 cites W2120733017 @default.
• W1995184116 cites W4253815822 @default.
• W1995184116 doi "https://doi.org/10.1159/000072705" @default.
• W1995184116 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12897465" @default.
• W1995184116 hasPublicationYear "2003" @default.
• W1995184116 type Work @default.
• W1995184116 sameAs 1995184116 @default.
• W1995184116 citedByCount "44" @default.
• W1995184116 countsByYear W19951841162012 @default.
• W1995184116 countsByYear W19951841162013 @default.
• W1995184116 countsByYear W19951841162014 @default.
• W1995184116 countsByYear W19951841162015 @default.
• W1995184116 countsByYear W19951841162017 @default.
• W1995184116 countsByYear W19951841162018 @default.
• W1995184116 countsByYear W19951841162019 @default.
• W1995184116 countsByYear W19951841162020 @default.
• W1995184116 countsByYear W19951841162022 @default.
• W1995184116 countsByYear W19951841162023 @default.
• W1995184116 crossrefType "journal-article" @default.
• W1995184116 hasAuthorship W1995184116A5008500153 @default.
• W1995184116 hasAuthorship W1995184116A5027281956 @default.
• W1995184116 hasAuthorship W1995184116A5034553302 @default.
• W1995184116 hasAuthorship W1995184116A5038452939 @default.
• W1995184116 hasAuthorship W1995184116A5051130816 @default.
• W1995184116 hasBestOaLocation W19951841161 @default.
• W1995184116 hasConcept C104849204 @default.
• W1995184116 hasConcept C123915805 @default.
• W1995184116 hasConcept C126322002 @default.
• W1995184116 hasConcept C134018914 @default.
• W1995184116 hasConcept C137061746 @default.
• W1995184116 hasConcept C170493617 @default.
• W1995184116 hasConcept C185592680 @default.
• W1995184116 hasConcept C202751555 @default.
• W1995184116 hasConcept C2776885963 @default.
• W1995184116 hasConcept C2778063415 @default.
• W1995184116 hasConcept C2778122271 @default.
• W1995184116 hasConcept C2778534260 @default.
• W1995184116 hasConcept C2780708007 @default.
• W1995184116 hasConcept C2780959883 @default.
• W1995184116 hasConcept C2908929049 @default.
• W1995184116 hasConcept C55493867 @default.
• W1995184116 hasConcept C71924100 @default.
• W1995184116 hasConcept C98274493 @default.
• W1995184116 hasConceptScore W1995184116C104849204 @default.
• W1995184116 hasConceptScore W1995184116C123915805 @default.
• W1995184116 hasConceptScore W1995184116C126322002 @default.
• W1995184116 hasConceptScore W1995184116C134018914 @default.
• W1995184116 hasConceptScore W1995184116C137061746 @default.
• W1995184116 hasConceptScore W1995184116C170493617 @default.
• W1995184116 hasConceptScore W1995184116C185592680 @default.
• W1995184116 hasConceptScore W1995184116C202751555 @default.
• W1995184116 hasConceptScore W1995184116C2776885963 @default.
• W1995184116 hasConceptScore W1995184116C2778063415 @default.
• W1995184116 hasConceptScore W1995184116C2778122271 @default.
• W1995184116 hasConceptScore W1995184116C2778534260 @default.
• W1995184116 hasConceptScore W1995184116C2780708007 @default.
• W1995184116 hasConceptScore W1995184116C2780959883 @default.
• W1995184116 hasConceptScore W1995184116C2908929049 @default.
• W1995184116 hasConceptScore W1995184116C55493867 @default.
• W1995184116 hasConceptScore W1995184116C71924100 @default.
• W1995184116 hasConceptScore W1995184116C98274493 @default.
• W1995184116 hasIssue "5" @default.
• W1995184116 hasLocation W19951841161 @default.
• W1995184116 hasLocation W19951841162 @default.
• W1995184116 hasOpenAccess W1995184116 @default.
• W1995184116 hasPrimaryLocation W19951841161 @default.
• W1995184116 hasRelatedWork W1974641745 @default.
• W1995184116 hasRelatedWork W2035737952 @default.
• W1995184116 hasRelatedWork W2040967247 @default.
• W1995184116 hasRelatedWork W2043032068 @default.
• W1995184116 hasRelatedWork W2049387452 @default.
• W1995184116 hasRelatedWork W2052640861 @default.
• W1995184116 hasRelatedWork W2069855804 @default.
• W1995184116 hasRelatedWork W2134709271 @default.
• W1995184116 hasRelatedWork W2158215753 @default.
• W1995184116 hasRelatedWork W4247631657 @default.
• W1995184116 hasVolume "23" @default.
• W1995184116 isParatext "false" @default.
• W1995184116 isRetracted "false" @default.
• W1995184116 magId "1995184116" @default.

• next