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• W1995205984 endingPage "293" @default.
• W1995205984 startingPage "281" @default.
• W1995205984 abstract "Signaling of transforming growth factor β (TGF-β) is mediated through a heteromeric complex of two types of transmembrane receptors and downstream intracellular proteins known as Smads. Alterations of TGF-β signaling underlie various forms of human cancer and developmental diseases. Human genetic studies have revealed both point mutations and deletions of Smad2 or Smad4 in several types of cancers. However, the role of Smad3 in tumorigenesis is not clear. Recent data indicate that Smad3 also functions as a tumor suppressor by inhibiting cell proliferation and promoting apoptosis. In addition, Smad3 is essential for TGF-β-mediated immune suppression, and it plays an important role in regulating transcriptional responses that are favorable to metastasis. Therefore, through regulating different transcriptional responses, Smad3 functions as both a negative and positive regulator of carcinogenesis depending on cell type and clinical stage of the tumor." @default.
• W1995205984 created "2016-06-24" @default.
• W1995205984 creator A5036125160 @default.
• W1995205984 creator A5046525796 @default.
• W1995205984 date "2007-01-01" @default.
• W1995205984 modified "2023-10-03" @default.
• W1995205984 title "Roles of Smad3 in TGF-β Signaling During Carcinogenesis" @default.
• W1995205984 cites W1484024717 @default.
• W1995205984 cites W1513470320 @default.
• W1995205984 cites W1530163318 @default.
• W1995205984 cites W1547534961 @default.
• W1995205984 cites W1565561072 @default.
• W1995205984 cites W1587849076 @default.
• W1995205984 cites W1897269170 @default.
• W1995205984 cites W1964742508 @default.
• W1995205984 cites W1966615054 @default.
• W1995205984 cites W1973047647 @default.
• W1995205984 cites W1976646363 @default.
• W1995205984 cites W1976738458 @default.
• W1995205984 cites W1985400766 @default.
• W1995205984 cites W1985929046 @default.
• W1995205984 cites W1986471913 @default.
• W1995205984 cites W1991088949 @default.
• W1995205984 cites W1995608083 @default.
• W1995205984 cites W2003907692 @default.
• W1995205984 cites W2003918448 @default.
• W1995205984 cites W2009128452 @default.
• W1995205984 cites W2009228099 @default.
• W1995205984 cites W2009629707 @default.
• W1995205984 cites W2014281832 @default.
• W1995205984 cites W2014888968 @default.
• W1995205984 cites W2017761226 @default.
• W1995205984 cites W2018077387 @default.
• W1995205984 cites W2018867485 @default.
• W1995205984 cites W2019788712 @default.
• W1995205984 cites W2020992760 @default.
• W1995205984 cites W2021183792 @default.
• W1995205984 cites W2022896763 @default.
• W1995205984 cites W2026428548 @default.
• W1995205984 cites W2026460094 @default.
• W1995205984 cites W2032927685 @default.
• W1995205984 cites W2034269086 @default.
• W1995205984 cites W2035653659 @default.
• W1995205984 cites W2036044995 @default.
• W1995205984 cites W2037038224 @default.
• W1995205984 cites W2037787006 @default.
• W1995205984 cites W2040074251 @default.
• W1995205984 cites W2040239915 @default.
• W1995205984 cites W2044954528 @default.
• W1995205984 cites W2051812986 @default.
• W1995205984 cites W2052813891 @default.
• W1995205984 cites W2057654378 @default.
• W1995205984 cites W2060606699 @default.
• W1995205984 cites W2060652817 @default.
• W1995205984 cites W2060810914 @default.
• W1995205984 cites W2061403592 @default.
• W1995205984 cites W2061476658 @default.
• W1995205984 cites W2069414088 @default.
• W1995205984 cites W2069524101 @default.
• W1995205984 cites W2072363222 @default.
• W1995205984 cites W2074604431 @default.
• W1995205984 cites W2076583198 @default.
• W1995205984 cites W2082438422 @default.
• W1995205984 cites W2082466352 @default.
• W1995205984 cites W2082867992 @default.
• W1995205984 cites W2084797427 @default.
• W1995205984 cites W2085419794 @default.
• W1995205984 cites W2085791588 @default.
• W1995205984 cites W2086692663 @default.
• W1995205984 cites W2087324367 @default.
• W1995205984 cites W2087988643 @default.
• W1995205984 cites W2091851050 @default.
• W1995205984 cites W2092513068 @default.
• W1995205984 cites W2095083228 @default.
• W1995205984 cites W2095515726 @default.
• W1995205984 cites W2095605427 @default.
• W1995205984 cites W2097829282 @default.
• W1995205984 cites W2099950968 @default.
• W1995205984 cites W2100522747 @default.
• W1995205984 cites W2102868284 @default.
• W1995205984 cites W2104976910 @default.
• W1995205984 cites W2107743402 @default.
• W1995205984 cites W2113613483 @default.
• W1995205984 cites W2113638068 @default.
• W1995205984 cites W2113989947 @default.
• W1995205984 cites W2115375679 @default.
• W1995205984 cites W2116217777 @default.
• W1995205984 cites W2116403488 @default.
• W1995205984 cites W2117200840 @default.
• W1995205984 cites W2118650242 @default.
• W1995205984 cites W2120724429 @default.
• W1995205984 cites W2122095304 @default.
• W1995205984 cites W2122686086 @default.
• W1995205984 cites W2125256208 @default.
• W1995205984 cites W2125374355 @default.
• W1995205984 cites W2129303004 @default.
• W1995205984 cites W2129379081 @default.
• W1995205984 cites W2129505749 @default.

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