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- W1995280178 abstract "✓ The effect of glycerol administration on cerebrospinal fluid (CSF) formation in dogs was studied by means of a ventriculocisternal perfusion technique. Net CSF production rate decreased after oral administration of glycerol (3 gm/kg) from a baseline level of 42.33 ± 6.68 µ l/min (mean ± standard error) to a trough of 10.33 ± 4.88 µ l/min at 90 minutes after administration (p < 0.025). Serum osmolality concomitantly increased from a baseline value of 296 ± 2.83 to 309 ± 4.7 mOsm/kg H 2 O at 90 minutes. The mean percentage change in CSF production inversely correlated to the mean percentage change in serum osmolality, r = −0.85. Thus, glycerol administration decreases net CSF formation, and this effect may be related in part to the rise in serum osmolality." @default.
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- W1995280178 date "1985-11-01" @default.
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- W1995280178 title "Acute effect of glycerol on net cerebrospinal fluid production in dogs" @default.
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- W1995280178 doi "https://doi.org/10.3171/jns.1985.63.5.0759" @default.
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