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- W1995296032 abstract "We previously reported that the expression of Ia antigens on cultured monolayers of murine thyroid epithelial cells (TEC) occurred with a particular distribution exclusively on the basal part of the cultured thyroid cells, while class I antigens of the major histocompatibility complex (MHC) are only detected on the apical surface. It appears that deposition of syngeneic lymphocytes induces, 24 h later, Ia expression on the apical side of cultured TEC, the surface that is in direct contact with the responder lymphocytes during syngeneic sensitization of T lymphocytes. We hypothesized that this phenomenon could represent, in syngeneic situations, the restriction process in antigen recognition by T cells, as demonstrated by Ia restricted primary syngeneic sensitization (PSS) on murine TEC." @default.
- W1995296032 created "2016-06-24" @default.
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- W1995296032 date "1985-01-01" @default.
- W1995296032 modified "2023-09-27" @default.
- W1995296032 title "Induction of Ia antigens on thyroid cultures by syngeneic T lymphocytes: A model of autoimmune disease" @default.
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- W1995296032 doi "https://doi.org/10.1016/0165-2478(85)90009-4" @default.
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