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- W1995348493 abstract "Ophthalmological Research Unit of the Medical Research Council, Institute of Ophthalmology, London. FEW subjects in opthalmology are more important from the clinical point of view than opacification and vascularization of the cornea; moreover, the problems included have a wide physiological and pathological interest. The unsatisfactory state of our present knowledge of the fundamental processes involved has been pointed out in the foregoing article by Ashton and Cook (1953), who also give a review of the literature. The present paper describes experimental investigations undertaken to elucidate these matters further. A new method of inducing a swelling and subsequent growth of vessels into the cornea has presented a unique opportunity for studying the underlying causes of these pathological phenomena. It has been shown (Langham, 1951) that a neutralized solution. of the organic compound alloxan, when brought into contact with the cornea of the rabbit, can be used to initiate either a completely reversible swelling of the cornea with little or no vascularization, or a swelling followed by a dense ingrowth of vessels around the whole periphery of the cornea. This method has been applied to the present problem in three ways:" @default.
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- W1995348493 date "1953-04-01" @default.
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- W1995348493 title "Observations on the Growth of Blood Vessels into the Cornea. Application of a New Experimental Technique" @default.
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- W1995348493 doi "https://doi.org/10.1136/bjo.37.4.210" @default.
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