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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995352927> ?p ?o ?g. }

• W1995352927 abstract "Sixty-two patients with pituitary dwarfism were treated with three different preparations of methionyl hGH (m-hGH) for 3 to 14 months. They were given 0.5 IU/kg/week intramuscularly. The growth rate during treatment with the three different preparations was the same for each and increased from 3.5 +/- 0.9 to 8.2 +/- 1.7 cm/year. A high incidence of hGH antibody formation was observed following the treatment, but the titer of antibody was decreased according to the purity of m-hGH preparations. At the end of 12 month treatment with a highly purified preparation (Somatonorm III), 76.2% of the patients had hGH antibody. However, the presence of antibodies did not affect the growth rate except in one patient. No clinical or laboratory side-effects were observed following the treatment with m-hGH. Thus, m-hGH was considered to be useful for the treatment of GH deficient children." @default.
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• W1995352927 date "1986-01-01" @default.
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• W1995352927 title "Treatment of pituitary dwarfism with methionyl human growth hormone in Japan." @default.
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• W1995352927 doi "https://doi.org/10.1507/endocrj1954.33.589" @default.
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