FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995366197> ?p ?o ?g. }

• W1995366197 endingPage "382" @default.
• W1995366197 startingPage "375" @default.
• W1995366197 abstract "Background Tumour stroma ratio (TSR) in histological sections of resected oesophageal adenocarcinomas proved to be a prognostic factor for patients’ survival. The objectives of this study were to assess inter- and intraobserver agreement for TSR scoring on biopsy material and to validate these biopsy results with the results derived from surgical specimens. Methods Biopsies and surgical specimens of 91 patients with oesophageal adenocarcinoma were available. TSR was determined on the original haematoxylin–eosin (H&E) tissue sections from primary tumour biopsies. To assess interobserver variation, TSR was scored by three pathologists as 0–25%, 25–50%, 50–75% or 75–100%. A second scoring was done to examine intraobserver variation. The definitive TSR biopsy score was compared with the corresponding resection specimen score. Kappa statistics were applied to evaluate agreement. Results Biopsies of 10 (11%) patients were rejected because of poor quality. For 81 TSR biopsy scores, interobserver correlations ranged between 0.239 and 0.486 (P < 0.001 for all). By classifying scores into two groups (<50% and ⩾50%), interobserver correlations ranged between 0.372 and 0.886 (P < 0.001 for all). Intraobserver agreement was substantial to near-perfect (κ = 0.780–0.848; P < 0.001 for all). Definitive TSR biopsy score showed moderate correlation with TSR scores on surgical specimens (κ = 0.506), but it was an independent prognostic factor for survival. Conclusion Reproducibility of tumour stroma ratio scoring on oesophageal adenocarcinoma biopsies was good. The ease of TSR scoring on H&E sections together with its correlation with patients’ survival may have clinical relevance in this era of neoadjuvant therapy." @default.
• W1995366197 created "2016-06-24" @default.
• W1995366197 creator A5025225016 @default.
• W1995366197 creator A5031930566 @default.
• W1995366197 creator A5061550014 @default.
• W1995366197 creator A5061565581 @default.
• W1995366197 creator A5068576761 @default.
• W1995366197 creator A5076811435 @default.
• W1995366197 creator A5077102606 @default.
• W1995366197 creator A5084788672 @default.
• W1995366197 date "2011-02-01" @default.
• W1995366197 modified "2023-10-12" @default.
• W1995366197 title "Reproducibility and validation of tumour stroma ratio scoring on oesophageal adenocarcinoma biopsies" @default.
• W1995366197 cites W1969450298 @default.
• W1995366197 cites W1990324485 @default.
• W1995366197 cites W1996858090 @default.
• W1995366197 cites W1998603067 @default.
• W1995366197 cites W2003681147 @default.
• W1995366197 cites W2008714016 @default.
• W1995366197 cites W2014371105 @default.
• W1995366197 cites W2034767173 @default.
• W1995366197 cites W2036410336 @default.
• W1995366197 cites W2037610714 @default.
• W1995366197 cites W2051642800 @default.
• W1995366197 cites W2052766041 @default.
• W1995366197 cites W2078502914 @default.
• W1995366197 cites W2089574951 @default.
• W1995366197 cites W2143718641 @default.
• W1995366197 cites W2164777277 @default.
• W1995366197 cites W2169996952 @default.
• W1995366197 cites W2170866914 @default.
• W1995366197 cites W3022237850 @default.
• W1995366197 cites W4252560545 @default.
• W1995366197 doi "https://doi.org/10.1016/j.ejca.2010.09.043" @default.
• W1995366197 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21036599" @default.
• W1995366197 hasPublicationYear "2011" @default.
• W1995366197 type Work @default.
• W1995366197 sameAs 1995366197 @default.
• W1995366197 citedByCount "50" @default.
• W1995366197 countsByYear W19953661972012 @default.
• W1995366197 countsByYear W19953661972013 @default.
• W1995366197 countsByYear W19953661972014 @default.
• W1995366197 countsByYear W19953661972015 @default.
• W1995366197 countsByYear W19953661972016 @default.
• W1995366197 countsByYear W19953661972017 @default.
• W1995366197 countsByYear W19953661972018 @default.
• W1995366197 countsByYear W19953661972019 @default.
• W1995366197 countsByYear W19953661972020 @default.
• W1995366197 countsByYear W19953661972021 @default.
• W1995366197 countsByYear W19953661972022 @default.
• W1995366197 countsByYear W19953661972023 @default.
• W1995366197 crossrefType "journal-article" @default.
• W1995366197 hasAuthorship W1995366197A5025225016 @default.
• W1995366197 hasAuthorship W1995366197A5031930566 @default.
• W1995366197 hasAuthorship W1995366197A5061550014 @default.
• W1995366197 hasAuthorship W1995366197A5061565581 @default.
• W1995366197 hasAuthorship W1995366197A5068576761 @default.
• W1995366197 hasAuthorship W1995366197A5076811435 @default.
• W1995366197 hasAuthorship W1995366197A5077102606 @default.
• W1995366197 hasAuthorship W1995366197A5084788672 @default.
• W1995366197 hasConcept C105795698 @default.
• W1995366197 hasConcept C121608353 @default.
• W1995366197 hasConcept C126322002 @default.
• W1995366197 hasConcept C126838900 @default.
• W1995366197 hasConcept C138885662 @default.
• W1995366197 hasConcept C142724271 @default.
• W1995366197 hasConcept C2775934546 @default.
• W1995366197 hasConcept C2776919888 @default.
• W1995366197 hasConcept C2778724333 @default.
• W1995366197 hasConcept C2781182431 @default.
• W1995366197 hasConcept C33923547 @default.
• W1995366197 hasConcept C41895202 @default.
• W1995366197 hasConcept C71924100 @default.
• W1995366197 hasConcept C74864618 @default.
• W1995366197 hasConcept C9893847 @default.
• W1995366197 hasConceptScore W1995366197C105795698 @default.
• W1995366197 hasConceptScore W1995366197C121608353 @default.
• W1995366197 hasConceptScore W1995366197C126322002 @default.
• W1995366197 hasConceptScore W1995366197C126838900 @default.
• W1995366197 hasConceptScore W1995366197C138885662 @default.
• W1995366197 hasConceptScore W1995366197C142724271 @default.
• W1995366197 hasConceptScore W1995366197C2775934546 @default.
• W1995366197 hasConceptScore W1995366197C2776919888 @default.
• W1995366197 hasConceptScore W1995366197C2778724333 @default.
• W1995366197 hasConceptScore W1995366197C2781182431 @default.
• W1995366197 hasConceptScore W1995366197C33923547 @default.
• W1995366197 hasConceptScore W1995366197C41895202 @default.
• W1995366197 hasConceptScore W1995366197C71924100 @default.
• W1995366197 hasConceptScore W1995366197C74864618 @default.
• W1995366197 hasConceptScore W1995366197C9893847 @default.
• W1995366197 hasIssue "3" @default.
• W1995366197 hasLocation W19953661971 @default.
• W1995366197 hasLocation W19953661972 @default.
• W1995366197 hasOpenAccess W1995366197 @default.
• W1995366197 hasPrimaryLocation W19953661971 @default.
• W1995366197 hasRelatedWork W165854754 @default.
• W1995366197 hasRelatedWork W1969855068 @default.
• W1995366197 hasRelatedWork W1995366197 @default.

• next