FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995397757> ?p ?o ?g. }

• W1995397757 endingPage "1375" @default.
• W1995397757 startingPage "1357" @default.
• W1995397757 abstract "The discovery of gene mutations responsible for autosomal dominant Alzheimer's disease has enabled researchers to reproduce in transgenic mice several hallmarks of this disorder, notably Aβ accumulation, though in most cases without neurofibrillary tangles. Mice expressing mutated and wild-type APP as well as C-terminal fragments of APP exhibit variations in exploratory activity reminiscent of behavioural and psychological symptoms of Alzheimer dementia (BPSD). In particular, open-field, spontaneous alternation, and elevated plus-maze tasks as well as aggression are modified in several APP transgenic mice relative to non-transgenic controls. However, depending on the precise murine models, changes in open-field and elevated plus-maze exploration occur in either direction, either increased or decreased relative to controls. It remains to be determined which neurotransmitter changes are responsible for this variability, in particular with respect to GABA, 5HT, and dopamine." @default.
• W1995397757 created "2016-06-24" @default.
• W1995397757 creator A5011054353 @default.
• W1995397757 creator A5020120789 @default.
• W1995397757 creator A5074570320 @default.
• W1995397757 date "2012-05-01" @default.
• W1995397757 modified "2023-10-18" @default.
• W1995397757 title "APP transgenic mice for modelling behavioural and psychological symptoms of dementia (BPSD)" @default.
• W1995397757 cites W10604852 @default.
• W1995397757 cites W1228255293 @default.
• W1995397757 cites W14396242 @default.
• W1995397757 cites W1479881183 @default.
• W1995397757 cites W1493435885 @default.
• W1995397757 cites W1511142149 @default.
• W1995397757 cites W1512881390 @default.
• W1995397757 cites W1513017963 @default.
• W1995397757 cites W1513919882 @default.
• W1995397757 cites W1540067873 @default.
• W1995397757 cites W1540282518 @default.
• W1995397757 cites W1546620272 @default.
• W1995397757 cites W154756152 @default.
• W1995397757 cites W1566528879 @default.
• W1995397757 cites W1572812739 @default.
• W1995397757 cites W1584834830 @default.
• W1995397757 cites W1595421068 @default.
• W1995397757 cites W1603841372 @default.
• W1995397757 cites W1619610860 @default.
• W1995397757 cites W1884657117 @default.
• W1995397757 cites W1886575365 @default.
• W1995397757 cites W1918909705 @default.
• W1995397757 cites W1919811763 @default.
• W1995397757 cites W1929267935 @default.
• W1995397757 cites W1933673012 @default.
• W1995397757 cites W1964215424 @default.
• W1995397757 cites W1964747897 @default.
• W1995397757 cites W1965100276 @default.
• W1995397757 cites W1965263019 @default.
• W1995397757 cites W1965275873 @default.
• W1995397757 cites W1966387980 @default.
• W1995397757 cites W1966984711 @default.
• W1995397757 cites W1967464880 @default.
• W1995397757 cites W1968001391 @default.
• W1995397757 cites W1968014528 @default.
• W1995397757 cites W1968168309 @default.
• W1995397757 cites W1968780740 @default.
• W1995397757 cites W1969424555 @default.
• W1995397757 cites W1969494696 @default.
• W1995397757 cites W1970029471 @default.
• W1995397757 cites W1971199242 @default.
• W1995397757 cites W1971529170 @default.
• W1995397757 cites W1971946214 @default.
• W1995397757 cites W1972067663 @default.
• W1995397757 cites W1972163528 @default.
• W1995397757 cites W1972461003 @default.
• W1995397757 cites W1972476800 @default.
• W1995397757 cites W1972565866 @default.
• W1995397757 cites W1972784541 @default.
• W1995397757 cites W1972850922 @default.
• W1995397757 cites W1973017204 @default.
• W1995397757 cites W1974311360 @default.
• W1995397757 cites W1975314522 @default.
• W1995397757 cites W1975627206 @default.
• W1995397757 cites W1976128767 @default.
• W1995397757 cites W1977653833 @default.
• W1995397757 cites W1977683347 @default.
• W1995397757 cites W1977809930 @default.
• W1995397757 cites W1978470814 @default.
• W1995397757 cites W1980482699 @default.
• W1995397757 cites W1980612924 @default.
• W1995397757 cites W1981288814 @default.
• W1995397757 cites W1982373527 @default.
• W1995397757 cites W1982654768 @default.
• W1995397757 cites W1983135376 @default.
• W1995397757 cites W1983282794 @default.
• W1995397757 cites W1983412249 @default.
• W1995397757 cites W1983432271 @default.
• W1995397757 cites W1983670592 @default.
• W1995397757 cites W1983857100 @default.
• W1995397757 cites W1984865373 @default.
• W1995397757 cites W1986576876 @default.
• W1995397757 cites W1988210470 @default.
• W1995397757 cites W1989453879 @default.
• W1995397757 cites W1991435932 @default.
• W1995397757 cites W1991838815 @default.
• W1995397757 cites W1992484817 @default.
• W1995397757 cites W1993339524 @default.
• W1995397757 cites W1993481893 @default.
• W1995397757 cites W1993710449 @default.
• W1995397757 cites W1993883271 @default.
• W1995397757 cites W1994092895 @default.
• W1995397757 cites W1994101711 @default.
• W1995397757 cites W1995272082 @default.
• W1995397757 cites W1995344309 @default.
• W1995397757 cites W1995426930 @default.
• W1995397757 cites W1995771314 @default.
• W1995397757 cites W1996332790 @default.
• W1995397757 cites W1996447834 @default.
• W1995397757 cites W1996658631 @default.

• next