FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995408087> ?p ?o ?g. }

• W1995408087 endingPage "776" @default.
• W1995408087 startingPage "770" @default.
• W1995408087 abstract "Summary Objective Recently, focal brain cooling ( FBC ) was proposed as a method for treating refractory epilepsy. However, the precise influence of cooling on the molecular basis of epilepsy has not been elucidated. Thus the aim of this study was to assess the effect of FBC on glutamate (Glu) concentration, cerebral blood flow ( CBF ), and glucose metabolism in patients with intractable epilepsy. Methods Nine patients underwent FBC at 15°C for 30 min prior to cortical resection (n = 6) or hippocampectomy (n = 3). Measurement of metabolites and CBF , as well as electrocorticography ( EC oG), was performed. Results Epileptic discharge ( ED ), as observed by EC oG, disappeared in the cooling period and reappeared in the rewarming period. Glu concentrations were high during the precooling period and were reduced to 51.2% during the cooling period (p = 0.025). Glycerol levels showed a similar decrease (p = 0.028). Lactate concentration was high during the precooling period and was reduced during the cooling period (21.3% decrease; p = 0.005). Glucose and pyruvate levels were maintained throughout the procedure. Changes in CBF were parallel to those observed by EC oG. Significance FBC reduced ED s and concentrations of Glu and glycerol. This demonstrates the neuroprotective effect of FBC . Our findings confirm that FBC is a reasonable and optimal treatment option for patients with intractable epilepsy. A PowerPoint slide summarizing this article is available for download in the Supporting Information section here ." @default.
• W1995408087 created "2016-06-24" @default.
• W1995408087 creator A5000597691 @default.
• W1995408087 creator A5010442242 @default.
• W1995408087 creator A5014355327 @default.
• W1995408087 creator A5027581199 @default.
• W1995408087 creator A5030350408 @default.
• W1995408087 creator A5037661411 @default.
• W1995408087 creator A5070738810 @default.
• W1995408087 creator A5072437205 @default.
• W1995408087 creator A5072891548 @default.
• W1995408087 creator A5073328436 @default.
• W1995408087 creator A5073917431 @default.
• W1995408087 creator A5076073242 @default.
• W1995408087 creator A5088430785 @default.
• W1995408087 creator A5091881914 @default.
• W1995408087 date "2014-04-29" @default.
• W1995408087 modified "2023-10-11" @default.
• W1995408087 title "Changes in glutamate concentration, glucose metabolism, and cerebral blood flow during focal brain cooling of the epileptogenic cortex in humans" @default.
• W1995408087 cites W1498507525 @default.
• W1995408087 cites W1512286671 @default.
• W1995408087 cites W1589490597 @default.
• W1995408087 cites W1628062902 @default.
• W1995408087 cites W1987133109 @default.
• W1995408087 cites W1989236873 @default.
• W1995408087 cites W1992742340 @default.
• W1995408087 cites W2011176528 @default.
• W1995408087 cites W2015222074 @default.
• W1995408087 cites W2016246099 @default.
• W1995408087 cites W2019175330 @default.
• W1995408087 cites W2023350356 @default.
• W1995408087 cites W2030663705 @default.
• W1995408087 cites W2036908864 @default.
• W1995408087 cites W2058107876 @default.
• W1995408087 cites W2064727978 @default.
• W1995408087 cites W2086711964 @default.
• W1995408087 cites W2091028973 @default.
• W1995408087 cites W2097135161 @default.
• W1995408087 cites W2103722437 @default.
• W1995408087 cites W2105727230 @default.
• W1995408087 cites W2115307720 @default.
• W1995408087 cites W2116394679 @default.
• W1995408087 cites W2120567673 @default.
• W1995408087 cites W2128826387 @default.
• W1995408087 cites W2130942587 @default.
• W1995408087 cites W2149809984 @default.
• W1995408087 cites W2159046062 @default.
• W1995408087 cites W2159832092 @default.
• W1995408087 cites W2169852210 @default.
• W1995408087 cites W4245264886 @default.
• W1995408087 doi "https://doi.org/10.1111/epi.12600" @default.
• W1995408087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24779587" @default.
• W1995408087 hasPublicationYear "2014" @default.
• W1995408087 type Work @default.
• W1995408087 sameAs 1995408087 @default.
• W1995408087 citedByCount "25" @default.
• W1995408087 countsByYear W19954080872014 @default.
• W1995408087 countsByYear W19954080872015 @default.
• W1995408087 countsByYear W19954080872016 @default.
• W1995408087 countsByYear W19954080872017 @default.
• W1995408087 countsByYear W19954080872018 @default.
• W1995408087 countsByYear W19954080872019 @default.
• W1995408087 countsByYear W19954080872020 @default.
• W1995408087 countsByYear W19954080872021 @default.
• W1995408087 countsByYear W19954080872022 @default.
• W1995408087 countsByYear W19954080872023 @default.
• W1995408087 crossrefType "journal-article" @default.
• W1995408087 hasAuthorship W1995408087A5000597691 @default.
• W1995408087 hasAuthorship W1995408087A5010442242 @default.
• W1995408087 hasAuthorship W1995408087A5014355327 @default.
• W1995408087 hasAuthorship W1995408087A5027581199 @default.
• W1995408087 hasAuthorship W1995408087A5030350408 @default.
• W1995408087 hasAuthorship W1995408087A5037661411 @default.
• W1995408087 hasAuthorship W1995408087A5070738810 @default.
• W1995408087 hasAuthorship W1995408087A5072437205 @default.
• W1995408087 hasAuthorship W1995408087A5072891548 @default.
• W1995408087 hasAuthorship W1995408087A5073328436 @default.
• W1995408087 hasAuthorship W1995408087A5073917431 @default.
• W1995408087 hasAuthorship W1995408087A5076073242 @default.
• W1995408087 hasAuthorship W1995408087A5088430785 @default.
• W1995408087 hasAuthorship W1995408087A5091881914 @default.
• W1995408087 hasBestOaLocation W19954080871 @default.
• W1995408087 hasConcept C126322002 @default.
• W1995408087 hasConcept C134018914 @default.
• W1995408087 hasConcept C15744967 @default.
• W1995408087 hasConcept C157767197 @default.
• W1995408087 hasConcept C158846371 @default.
• W1995408087 hasConcept C169760540 @default.
• W1995408087 hasConcept C170493617 @default.
• W1995408087 hasConcept C185592680 @default.
• W1995408087 hasConcept C2778186239 @default.
• W1995408087 hasConcept C2780117969 @default.
• W1995408087 hasConcept C2780881558 @default.
• W1995408087 hasConcept C42219234 @default.
• W1995408087 hasConcept C55493867 @default.
• W1995408087 hasConcept C61174792 @default.
• W1995408087 hasConcept C71924100 @default.
• W1995408087 hasConceptScore W1995408087C126322002 @default.

• next