Matches in SemOpenAlex for { <https://semopenalex.org/work/W1995451723> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W1995451723 endingPage "855" @default.
- W1995451723 startingPage "849" @default.
- W1995451723 abstract "Purified human Ia molecules were labelled with maleimide or isothiocyanate spin labels or by reacting “TEMPAMINE” spin label with the neuraminic acid of their carbohydrate residues. It was found that increasing the ionic strength from 0.05 to 0.75 markedly increased the dipolar interaction between the maleimide-attached labels, but no effect was found of ionic strength or motion on dipolar interaction with the other two labels. The effect of increasing ionic strength could be blocked by the prior addition of la-specific antibody, but could not be reversed by the addition of antibody after the ionic strength was increased. These findings complement an earlier finding that increasing ionic strength over the range 0.05–0.75 has an inhibitory effect on the combination of Ia with its antibody. Because the maleimide spin labels attach predominantly to SH groups it is suggested that increasing ionic strength causes conformational changes in the immunoglobulin loop region which alter the accessibility of the Ia antibody-binding site." @default.
- W1995451723 created "2016-06-24" @default.
- W1995451723 creator A5013182948 @default.
- W1995451723 creator A5016431770 @default.
- W1995451723 creator A5045408318 @default.
- W1995451723 date "1985-08-01" @default.
- W1995451723 modified "2023-10-16" @default.
- W1995451723 title "A spin label study of the ionic strength dependent conformational change in the human Ia molecule" @default.
- W1995451723 cites W1879681770 @default.
- W1995451723 cites W1980266972 @default.
- W1995451723 cites W1984156045 @default.
- W1995451723 cites W1987503272 @default.
- W1995451723 cites W1989941778 @default.
- W1995451723 cites W2008004106 @default.
- W1995451723 cites W2009462251 @default.
- W1995451723 cites W2014002422 @default.
- W1995451723 cites W2034847171 @default.
- W1995451723 cites W2045832806 @default.
- W1995451723 cites W2083818319 @default.
- W1995451723 cites W2090419804 @default.
- W1995451723 cites W2092247667 @default.
- W1995451723 cites W2146791465 @default.
- W1995451723 cites W2207584063 @default.
- W1995451723 cites W2229737375 @default.
- W1995451723 cites W2431429215 @default.
- W1995451723 cites W2480702252 @default.
- W1995451723 doi "https://doi.org/10.1016/0161-5890(85)90069-0" @default.
- W1995451723 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2413347" @default.
- W1995451723 hasPublicationYear "1985" @default.
- W1995451723 type Work @default.
- W1995451723 sameAs 1995451723 @default.
- W1995451723 citedByCount "2" @default.
- W1995451723 crossrefType "journal-article" @default.
- W1995451723 hasAuthorship W1995451723A5013182948 @default.
- W1995451723 hasAuthorship W1995451723A5016431770 @default.
- W1995451723 hasAuthorship W1995451723A5045408318 @default.
- W1995451723 hasConcept C145148216 @default.
- W1995451723 hasConcept C178790620 @default.
- W1995451723 hasConcept C184651966 @default.
- W1995451723 hasConcept C185592680 @default.
- W1995451723 hasConcept C187428577 @default.
- W1995451723 hasConcept C2182769 @default.
- W1995451723 hasConcept C2780105360 @default.
- W1995451723 hasConcept C2780115458 @default.
- W1995451723 hasConcept C32909587 @default.
- W1995451723 hasConcept C41625074 @default.
- W1995451723 hasConcept C55493867 @default.
- W1995451723 hasConcept C79123411 @default.
- W1995451723 hasConcept C8010536 @default.
- W1995451723 hasConceptScore W1995451723C145148216 @default.
- W1995451723 hasConceptScore W1995451723C178790620 @default.
- W1995451723 hasConceptScore W1995451723C184651966 @default.
- W1995451723 hasConceptScore W1995451723C185592680 @default.
- W1995451723 hasConceptScore W1995451723C187428577 @default.
- W1995451723 hasConceptScore W1995451723C2182769 @default.
- W1995451723 hasConceptScore W1995451723C2780105360 @default.
- W1995451723 hasConceptScore W1995451723C2780115458 @default.
- W1995451723 hasConceptScore W1995451723C32909587 @default.
- W1995451723 hasConceptScore W1995451723C41625074 @default.
- W1995451723 hasConceptScore W1995451723C55493867 @default.
- W1995451723 hasConceptScore W1995451723C79123411 @default.
- W1995451723 hasConceptScore W1995451723C8010536 @default.
- W1995451723 hasIssue "8" @default.
- W1995451723 hasLocation W19954517231 @default.
- W1995451723 hasLocation W19954517232 @default.
- W1995451723 hasOpenAccess W1995451723 @default.
- W1995451723 hasPrimaryLocation W19954517231 @default.
- W1995451723 hasRelatedWork W1521670899 @default.
- W1995451723 hasRelatedWork W1990798553 @default.
- W1995451723 hasRelatedWork W1995451723 @default.
- W1995451723 hasRelatedWork W2022870463 @default.
- W1995451723 hasRelatedWork W2062684751 @default.
- W1995451723 hasRelatedWork W2072712095 @default.
- W1995451723 hasRelatedWork W2087052575 @default.
- W1995451723 hasRelatedWork W2392101069 @default.
- W1995451723 hasRelatedWork W2783351236 @default.
- W1995451723 hasRelatedWork W2998977823 @default.
- W1995451723 hasVolume "22" @default.
- W1995451723 isParatext "false" @default.
- W1995451723 isRetracted "false" @default.
- W1995451723 magId "1995451723" @default.
- W1995451723 workType "article" @default.